An analogue of neurodiclovit in tablets. Neurodiclovitis: analogues of the drug, cheaper, with the same composition

Composition and release forms

• Titanium dioxide;
• Gelatin;
• Iron oxide red;
• Iron oxide yellow;
• Povidone;
• Copolymer of methacrylic acid and ethyl acrylate (Eudragit NE30D);
• Silicone antifoam SE2 MC;
• Talc;
• Triethyl acetate.

Neurodiclovit capsules have a gelatinous shell, the body of which is painted pink-yellow, and the lid is brown. The capsules contain a mixture of white granules (diclofenac) and pink powder (B vitamins) inside. The capsules are available in packs of 30.

From what the drug Neurodiclovit (therapeutic effect)

Indications for use

• Post-injury period;
• The period after surgery;
• The period after dental interventions (for example, tooth extraction, cleaning of gum pockets, etc.);
• Gynecological diseases of a non-infectious nature, for example, pain during menstruation, adnexitis, etc.;
• Inflammatory diseases of the ENT organs - pharyngitis, tonsillitis, otitis media, sinusitis, etc.

2. Reducing the severity and volume of inflammation, as well as relief of pain in inflammatory and degenerative diseases of the joints and spine:

• Chronic polyarthritis;
• Rheumatic arthritis;
• Rheumatoid arthritis;
• Ankylosing spondylitis;
• Osteoarthritis;
• Spondyloarthrosis;
• Acute gouty arthritis.

3. Relief of pain and inflammation in the following diseases of the nervous system:

• Cervical syndrome;
• Lumbago;
• Sciatica.

4. Rheumatic lesions of soft tissues (muscles, connective tissue, etc.).

Neurodiclovitis - instructions for use

General Provisions

Pregnancy and breastfeeding

special instructions

Influence on the ability to control mechanisms

Overdose

• Myoclonic convulsions;
• Nausea;
• Stomach ache;
• Bleeding from the organs of the gastrointestinal tract;
• Dysfunction of the liver and kidneys (including liver or kidney failure).

To treat an overdose, you should first flush the stomach, then take a sorbent (for example, activated carbon, Polysorb, Polyphepan, Filtrum, Lactofiltrum, etc.). After that, drink plenty of fluids and diuretics (Furosemide) to ensure the fastest elimination of the drug from the body. If necessary, symptomatic therapy is carried out, aimed at maintaining the normal functioning of vital organs.

Interaction with other drugs

Neurodiclovitis and alcohol

Side effects

• Headache;
• Dizziness;
• Sleep disturbance;
• Drowsiness;
• Depression;
• Irritability;
• Aseptic meningitis (usually in people with systemic lupus erythematosus or other connective tissue diseases);
• Seizures;
• General weakness;
• Disorientation;
• Nightmares;
• Fears.

3.From the senses:

• Noise in ears;
• Blurred vision;
• Diplopia (double vision);
• Disturbance of taste;
• Hearing impairment, which may be reversible or irreversible;
• Scotoma.

4.On the part of the skin and soft tissues:

• Fluid retention in the body;
• Nephrotic syndrome;
• Proteinuria (protein in the urine);
• Oliguria (decrease in the amount of urine excreted);
• Hematuria (blood in the urine)
• Interstitial nephritis;
• Papillary necrosis;
• Acute renal failure
• Azotemia (the level of residual nitrogen in the blood is higher than normal);
• Decreased libido.

6.Blood system:

• Anemia;
• Leukopenia (the total number of blood leukocytes is below normal);
• Thrombocytopenia (the total number of platelets in the blood is below normal);
• Eosinophilia (the number of eosinophils in the blood is higher than normal);
• Agranulocytosis (absence of neutrophils, basophils and eosinophils in the blood);
• Thrombocytopenic purpura;
• Aggravation of the course of chronic infectious diseases.

7.

Contraindications for use

• Individual hypersensitivity or allergic reactions to any components of the drug;
• Individual hypersensitivity or allergic reactions to any drugs of the NSAID group (for example, Ibuprofen, Nurofen, Paracetamol, Nimesulide, Nimesil, Nise, Ketorol, etc.);
• The period of exacerbation of erosive and ulcerative lesions of the digestive tract;
• Gastrointestinal bleeding;
• Intracranial hemorrhage;
• Bronchial asthma, combined with polyps of the nasal mucosa;
• Violation of hematopoiesis;
• Blood clotting disorders;
• Progressive liver or kidney disease;
• Severe liver failure;
• Renal failure with creatinine clearance less than 30 ml / min;
• Severe heart failure;
• The period after the operation of coronary artery bypass grafting;
• Hyperkalemia (potassium levels in the blood are higher than normal);
• The period of pregnancy and breastfeeding;
• Age under 18.

In addition to the indicated absolute contraindications to the use of Neurodiclovit, there are also relative ones. Relative contraindications include conditions or diseases in which the drug is not prohibited to use, but this should be done with caution, only if indicated and under the supervision of a physician. Relative contraindications to the use of Neurodiclovit include the following conditions or diseases:

• Anemia;
• Bronchial asthma;
• Congestive heart failure;
• Arterial hypertension;
• Ischemic heart disease (CHD);
• Cerebrovascular diseases (for example, cerebrovascular accident, increased intracranial pressure, etc.);
• Concomitant use of glucocorticosteroids (Prednisolone, Dexamethasone, etc.), anticoagulants (Warfarin, Dikumarin, etc.), antiplatelet agents (Clopidogrel, etc.), selective serotonin reuptake inhibitors (Citalopram, Alprazolam, etc.)
• Dyslipidemia or hyperlipidemia (elevated cholesterol levels or abnormal concentrations of its fractions);
• Diabetes;
• Peripheral artery disease;
• Helicobacteriosis;
• Long-term use of drugs of the NSAID group (Aspirin, Ibuprofen, Nimesulide, Nurofen, Ketorol, etc.);
• Swelling;
• Renal or hepatic impairment;
• Alcoholism;
• Smoking;
• Inflammatory bowel disease (colitis, enteritis, duodenitis, etc.);
• Diverticulitis;
• The stage of remission of erosive and ulcerative lesions of the gastrointestinal tract;
• Condition after extensive surgical operations;
• Induced porphyria;
• Low blood volume (for example, after vomiting, diarrhea, sweating, or other situations where the body is losing fluid);
• Elderly age (over 65);
• Systemic connective tissue diseases (systemic lupus erythematosus, scleroderma, dermatomyositis, etc.).

Neurodiclovitis - analogues

So, the following drugs are analogs of Neurodiclovit in the domestic pharmaceutical market:

• Arthrotek tablets;
• Bioran tablets and injection;
• Voltaren tablets, injection and rectal suppositories;
• Voltaren Acti tablets;
• Voltaren Rapid tablets and powder for oral solution;
• Diclac tablets, injection and rectal suppositories;
• Diklovit rectal suppositories;
• Diclogen tablets and injection;
• Diclonat P tablets, injection and rectal suppositories;
• Dicloran tablets and injection;
• Dicloran SR tablets;
• Diclofenac tablets, solution and rectal suppositories;
• Diclofenac bufus solution for injection;
• Diclofenac retard extended-release tablets;
• Dolomin injection solution;
• Naklofen tablets, solution and rectal suppositories;
• Naklofen Duo Modified Release Capsules;
• Naklofen SR tablets of prolonged action;
• Naklofen Protect set of capsules;
• Ortofen tablets and injection;
• Ortofer tablets and injection solution;
• Panoxen tablets;
• Rapten Duo and Rapten Rapid tablets;
• SwissJet and SwissJet Duo capsules;
• Tabuk-Dee pills;
• Flotak capsules.

Reviews

Neurodiclovitis or Neuromultivitis?

Price in Russia and Ukraine

• 30 capsules of Neurodiclovit - 245 - 326 rubles or 108 - 161 hryvnia.

Cheap analogues and substitutes for the drug neurodiclovit: a list with prices

The medication can not only eliminate pain, but also alleviate the condition with such ailments as:

• arthrosis;
• chronic polyarthritis;
• neuritis;
• ankylosing spondylitis;
• spondylitis;
• extra-articular soft tissue rheumatism;
• acute gouty arthritis.

The drug is produced in the form of capsules, which are intended for oral administration. They are placed in blisters of 10 pieces.

The carton contains 3 blisters. The capsule contains a white powder, its active ingredient is sodium diclofenac, and also contains a pink powder with several active elements - vitamins B1, B6 and B12.

The cost of the drug Neurodiclovit is average. You can buy a package of the medication for 300 rubles.

Analogues of Russian production

Neurodiclovitis refers to drugs with an average price, but many still do not want to overpay, for this reason they are looking for close substitutes of Russian production with a low price.

Before replacing it with a cheap analogue, it is worth examining possible analogs.

Below is a table with Russian-made substitutes:

Analogs of Neurodiclovit capsules

Manufacturer: Lannacher Heilmittel GmbH (Austria)

Advantageous substitutes for Neurodiclovitis in capsules

An analogue is cheaper from 261 rubles.

Manufacturer: Synthesis AKOMP

An analogue is cheaper from 261 rubles.

Manufacturer: Pharmstandard-Leksredstva (Russia)

An analogue is cheaper from 243 rubles.

Manufacturer: Dr Reddy`s (India)

Analogue is cheaper from 232 rubles.

Producer: Salutas Pharma GmbH (Germany)

An analogue is cheaper from 226 rubles.

Manufacturer: Ranbaxi (India)

Release forms:

• Tablets 10 mg. 20 pcs.; Price from 67 rubles
• Tablets 10 mg. 100 pieces.; Price from 299 rubles

Prices for Ketans in online pharmacies

How to choose a substitute for the drug Neurodiclovit?

Neurodiclovitis and its analogues quickly and effectively eliminate pain in diseases of the musculoskeletal system. Neurodiclovitis is a combined drug from the Austrian company Gerot Lannach Pharma. The drug consists of sodium diclofenac and B vitamins.

For example, with osteochondrosis of the spine, which affects more than half of humanity, severe back pain may occur. Because of it, a person literally freezes in one position, since an attempt to make any movement will only increase the pain. This condition is a consequence of the compression of the spinal nerves. This is the result of degenerative cartilage damage and reactive changes occurring in the vertebrae.

What are Neurodiclovit and its analogues used for?

Neurodiclovitis is easy to use, as it saves the patient from taking a number of drugs and shortens the duration of treatment. Research results have shown that when using B vitamins with diclofenac, pain goes away faster. And since diclofenac has many side effects, it is preferable to take a shorter course of treatment with this medicine. In this case, this drug is the most suitable remedy for dealing with disorders of the musculoskeletal system and the nervous system.

Diseases for which this drug is indicated:

The drug is also used when the temperature rises, the formation of edema and swelling.

Each capsule contains:

• diclofenac (50 mg) - active ingredient;
• vitamin B1 (thiamine hydrochloride);
• vitamin B6 (pyridoxine hydrochloride);
• vitamin B12 (cyanocobalamin);
• auxiliary components.

Similar drugs

There are no analogues that would simultaneously include B vitamins and NSAIDs. Therefore, if necessary, the most suitable substitutes are selected.

Similar drugs, trade names of which sound different, but they have the same basic substance, which can replace Neurodiclovit:

• Arthrotek;
• Bioran;
• Voltaren;
• Voltaren Acti;
• Voltaren Rapid - powder, a suspension is prepared from it;
• Diklak;
• Diklovit;
• Diclogen;
• Diclonat;
• Dicloran;
• Dicloran SR;
• Diclofenac;
• Diclofenac Bufus - solution for injection;
• Diclofenac Retard - long-acting tablets;
• Dolomin;
• Naklofen;
• Naklofen Duo - modified release capsules;
• Naklofen SR - long-acting tablets;
• Naklofen Protect;
• Ortofen;
• Panoxen;
• Rapten Duo;
• Rapten Rapid;
• Swiss Jet Duo;
• Tabuk Dee;
• Flotak;
• Movalis;
• Meloxicam;
• Ketorolac;
• Tenoxicam;
• Lornoxicam.

In different drugs, the dose of diclofenac is different, therefore, when choosing an analogue, this fact must be taken into account. Since each drug has its own specifics and contraindications, a doctor's consultation is required.

Treatment with Neurodiclovitis is often continued with Neuromultivitis. This drug contains similar vitamins, but without diclofenac. Neuromultivitis is prescribed for the treatment of neurological diseases. When the question of replacing Neurodiclovitis arises, the fact of the presence of neuritis is taken into account. If such therapy is needed, then Neuromultivitis can be used instead of Neurodiclovitis.

1. Thiamine (B1) - participates in metabolic processes and the transport of nerve impulses.
2. Pyridoskin (B6) - is found in substances responsible for the functioning of the nervous system. These include dopamine, adrenaline, serotonin, histamine. All of them provide the normal state of the nervous tissue.
3. Cyanocobalamin (B 12) - has a positive effect on the blood, in particular on the formation of red blood cells in the bone marrow, promotes the renewal of nerve cells.

In complex treatment, these vitamins enhance the properties of diclofenac. Thanks to this, this combination of drugs quickly relieves neuralgic pain.

Who is appointed

Also indications for use are:

1. Post-traumatic pain.
2. The rehabilitation period after surgery.
3. Dental treatment.
4. Gynecological pains that are not of an infectious nature.
5. Respiratory diseases.

All non-steroidal drugs have side effects, and diclofenac is no exception.

Possible side reactions

• flatulence and abdominal pain;
• stool disorder - diarrhea or constipation;
• nausea and urge to vomit;
• overworked liver;
• jaundice.

From the side of the nervous system, the following side effects are possible:

• headache and dizziness;
• insomnia or increased sleepiness;
• increased nervous irritability;
• depression and stress;
• increased feeling of fear;
• lack of coordination;
• muscle cramps.

• extraneous tinnitus;
• deterioration of vision;
• change in taste;
• hearing impairment (this needs to be paid serious attention to, since after discontinuation of the drug, this phenomenon can become chronic).

• deterioration of kidney function;
• the appearance of edema;
• excretion of protein in the urine;
• reduction in the amount of urine excreted;
• the appearance of blood in the urine;
• decreased libido.

Complications from chronic diseases are possible.

• the appearance of a cough;
• spasms from the bronchi;
• pneumonia;
• laryngeal edema.

Contraindications for use

• hypersensitivity to any of the components contained in the drug;
• hypersensitivity to any non-steroidal drug;
• exacerbation of gastrointestinal diseases;
• bleeding (any);
• asthmatic cough;
• disorders of hematopoiesis (poor clotting);
• pathology of the kidneys or liver;
• heart problems;
• after open heart surgery;
• high levels of potassium in the blood;
• pregnancy;
• children and adolescents under 18;
• taking alcoholic beverages;
• diabetes.

Price difference

Often, when doctors prescribe drugs to a patient, the question arises of replacing drugs with more affordable ones. Many believe that Russian counterparts are cheaper because they are not subject to additional import duties.

The price for similar drugs produced by different companies can differ tenfold. And the buyer has a natural question, if the active substance is the same, then why is there such a difference in cost.

The manufacturer spends a lot of money on the original drug - research, advertising, etc. Therefore, the manufacturer tries to compensate for the losses by selling the drug at a high price. And generics are no longer being researched and are produced using the same technology, but under a different name.

The next aspect that significantly increases the price is packaging. The more beautiful and quality it is, the higher the price. But this does not affect the quality of the medicine. As for the choice between a domestic product and an imported one, it is known that foreign analogues are produced using higher technologies, therefore, the quality of such drugs is much higher.

Neurodiclovitis: instructions for use, indications, reviews and analogues

Neurodiclovitis is a drug that belongs to non-steroidal anti-inflammatory drugs, it contains diclofenac and B vitamins. Thanks to this combination of active substances, pains caused by neurological, musculoskeletal (sometimes gynecological and otolaryngic) diseases are reduced.

Diclofenac has anti-inflammatory, analgesic and antipyretic effects, also relieves swelling and swelling. The therapeutic effect is carried out by indiscriminate inhibition of cyclooxygenase-1 and cyclooxygenase-2, which causes a disruption in the metabolism of arachidonic acid and a decrease in prostaglandins (pain mediators) in the inflammatory focus. Thus, in rheumatic pathologies, taking the drug eliminates morning stiffness, relieves inflammation and swelling of the joint.

After injury and in the postoperative period, Neurodiclovitis reduces pain and swelling, and prevents the development of fever.

Neurodiclovitis, photo of capsules

B vitamins have the following effects:

1. Thiamine (B1). Participates in carbon, lipid, energy and protein metabolism, regulates the activity of the nervous system (in particular, it is responsible for the mechanism of nerve impulse conduction).

2. Pyroxidine (B6). Improves the contractility of the heart muscle, promotes the conversion of folic acid into the active form. Also, the vitamin is involved in the synthesis of neurotransmitters, regulates the work of the nervous system, promotes the absorption of glucose by nerve cells, reduces spasms and muscle cramps, and improves the passage of impulses from receptors to the brain. In addition, pyroxidine synthesizes neurotransmitters such as dopamine, serotonin, norepinephrine, epinephrine, and histamine.

3. Cyanocobalomin (B12). Participates in the hematopoietic process, the formation of neurons, has a positive effect on metabolism, synthesizes nucleic acids necessary for the normal functioning of the nervous system.

The medication is dispensed in capsules. Ingredients: diclofenac (50 milligrams), thiamine (50 milligrams), pyroxidine (50 milligrams), cyanocobalomin (1/4 milligram).

Indications for use

What is Neurodiclovitis used for? It is prescribed for the following diseases:

• Inflammatory and degenerative-dystrophic pathologies of the ridge and bone joints, accompanied by severe pain and inflammation (osteochondrosis, spondyloarthrosis, osteoarthritis, chronic polyarthritis);
• Neuritis (inflammation of the occipital, intercostal or facial nerves, as well as the nerves of the limb) and neuralgia (severe pain along the nerve innervation - sciatica, lumbago, trigeminal attack);
• Acute gouty arthritis;
• Rheumatic extra-articular damage to the periarticular tissues.

Also, the drug is prescribed if there is a pronounced pain syndrome after surgical or dental implantation, with painful menstruation, sore throat caused by angina, tonsillitis, pharyngitis.

Instructions for use Neurodiclovit, dosages

The drug is taken orally, the capsules are not chewed or opened. Drink plenty of water. Neurodiclovitis is recommended to be taken immediately after meals.

The dosage is prescribed by the attending physician on an individual basis. According to the instructions for use of Neurodiclovit, the recommended amount is:

1. For adults, one capsule three times a day, maintenance therapy - one capsule a day;
2. For adolescents (departure, if the body weight is more than 40 kg), one capsule twice a day, maintenance therapy - one capsule every other day;
3. Patients over 65 years of age require dosage adjustment. Before prescribing the medication, a detailed study of the function of the liver and kidneys is carried out.

If the indicators are slightly deviated to the side, then the dosage is prescribed, as for adolescents.

It should be borne in mind that the drug reduces the effect of diuretics, therefore, the risk of developing hyperkalemia (release of potassium from cells and the body) increases. If the patient is being treated with coagulants or thrombolytic drugs, then there is a high risk of hemorrhage (most often in the stomach or intestines). The effect of antihypertensive and sedatives is reduced if Neurodiclovit is used simultaneously with them.

Contraindications and overdose

The drug is not prescribed for the following diseases and features:

• intolerance to any component;
• a history of the aspirin triad (simultaneous aspirin intolerance, nasal polyps and bronchial asthma);
• porphyrin disease (violation of pigment metabolism);
• diseases of the blood and hematopoietic organs, including hemorrhagic diathesis (the body's tendency to bleed and hemorrhage);
• ulcer of the stomach and 12 duodenal ulcer (acute form), including perforation of the ulcer; Crohn's disease, bleeding in the stomach or intestines;
• heart failure (moderate to severe);
• thromboembolism, erythremia, erythrocytosis;
• allergic manifestations of moderate and severe severity.

Neurodiclovitis is also contraindicated in children under 12 years of age, women who are carrying a fetus and breastfeeding.

Relative contraindications include:

High blood pressure, ischemia, impaired peripheral and cerebral circulation;

Angina pectoris, malignant neoplasms.

During treatment, the patient may experience side effects of varying severity. Reactions to Neurodiclovitis are most often:

• heart and blood vessels (hypertension, fluid retention in the body, myocardial infarction, heart rhythm disturbances);
• from the side of the central nervous system - convulsive syndrome, sleep disturbance, migraine, trembling fingers, anxiety, deterioration in visual acuity;
• gastrointestinal system - the formation or progression of ulcers, abdominal pain, pathological changes in stool (diarrhea or constipation), flatulence;
• urinary system - failure of renal function, urinary retention, protein and hematuria;
• skin - small rash, focal redness, itching, severe hyperemia.

Overdose occurs when an incorrect dose of the drug is taken or as a result of prolonged treatment with it. The patient is diagnosed with renal failure and symptoms of hepatotoxicity (nausea, vomiting, yellowness of the skin). Also, an overdose leads to the development of neurotoxic symptoms (neuropathy, seizures, heart rhythm disturbances).

Analogues Neurodiclovit, list of drugs

Today there are many analogues of Neurodiclovitis, the most common are:

Important - the instructions for the use of Neurodiclovit, the price and reviews do not apply to analogues and cannot be used as a guide to the use of drugs of similar composition or action. All therapeutic appointments must be made by a doctor. When replacing Neurodiclovit with an analogue, it is important to consult a specialist, you may need to change the course of therapy, dosages, etc. Do not self-medicate!

Doctor's opinion about Neurodiclovite: “The medication perfectly relieves pain syndrome, it is sold in a pharmacy without a prescription, it can even be used as an ambulance at home. Nevertheless, due to the large list of contraindications, not every patient is prescribed, therefore it is necessary to prescribe analogs, the therapeutic effect of which is sometimes much worse. "

Nmedicine.net

Neurodiclovitis is a combined drug produced by the pharmaceutical company G.L. Pharma Austria. The drug has its own analogues, which you can familiarize yourself with below.

Description of the drug Neurodiclovit

The active ingredients of the drug Neurodiclovit are the following: pyridoxine hydrochloride (Pyridoxini hydrochloridum) - vit. В6, thiamine hydrochloride (Thiamin hydrochloride) - vit. B1, diclofenac sodium,

cyanocobalamin (Cyanocobalaminum) - vit. B12. In addition, Neurodiclovit contains additional components.

Neurodiclovit is produced in medicinal capsules.

The pharmacological action is created by the components included in this drug. Neurodiclovitis has anti-inflammatory, analgesic, antipyretic effects.

Neurodiclovitis is used in the following conditions:

• The appearance of pain syndrome in inflammatory processes of non-rheumatic origin;
• Consequences of trauma, surgical and dental operations;
• Gynecological diseases - adnexitis, primary algodismenorrhea;
• Inflammatory phenomena of the ENT organs - otitis media, tonsillitis, pharyngitis;
• Diseases of an inflammatory nature of the spine and joints - rheumatoid arthritis, rheumatoid arthritis, chronic polyarthritis, ankylosing spondylitis, spondyloarthrosis, osteoarthritis;
• Neuritis, neuralgia - lumbago, sciatica, cervical syndrome;
• Acute gouty arthritis;
• Soft tissue rheumatism.

Analogs

The most famous analogue of the drug Neurodiclovit is Diclofenac with the active substance diclofenac sodium, which has anti-inflammatory, analgesic, antipyretic and antiplatelet effects.

Analogues of the medicine NEURODICLOVIT

Analogues with the same active ingredient

• Arthrex gel for external use
• Veral gel for external use, enteric-coated tablets
• Voltaren plaster - transdermal therapeutic system, solution for intramuscular administration, metered spray for external use, rectal suppositories, enteric-coated tablets, coated tablets, prolonged action
• Voltaren Acti film-coated tablets
• Voltaren Ofta eye drops
• Voltaren rapid powder for solution for oral administration, film-coated tablets
• Voltaren Emulgel gel for external use
• Voltaren-Flotac capsules
• Diklak gel for external use, solution for intramuscular injection, rectal suppositories, prolonged-release tablets
• Diklak Lipogel gel for external use
• Diclo-F eye drops, enteric-coated tablets
• Diclobene gel for external use, solution for intramuscular administration
• Dicloberl N 75 solution for injection
• Diklovit gel for external use, rectal suppositories
• Diclogen gel for external use, solution for intramuscular administration, enteric-coated tablets, enteric-coated tablets, prolonged action
• Diklomax solution for intramuscular administration, enteric-coated tablets
• Diclomelan injection, suppositories, film-coated tablets, film-coated tablets, prolonged release
• Diclonac solution for intramuscular administration, enteric-coated tablets
• Diclonat P gel for external use, solution for intravenous and intramuscular administration, solution for intramuscular administration, film-coated tablets, prolonged action
• Dicloran gel for external use, solution for intramuscular administration, enteric-coated tablets
• Dicloran SR film-coated tablets, extended release
• Diclorium injection, tablets
• Diclofen solution for injection, suppositories, tablets, extended-release tablets
• Diclofenac gel for external use, eye drops, ointment for external use, solution for intramuscular administration, rectal suppositories, prolonged-release film-coated tablets, enteric-coated tablets, film-coated tablets, film-coated tablets, prolonged release, tablets coated with intestinal soluble membrane, prolonged action
• Diclofenac (Biclopan) enteric-coated tablets
• Diclofenac (Ortofen) enteric-coated tablets
• Diclofenac bufus solution for intramuscular administration
• Diclofenac potassium substance powder
• Diclofenac retard tablets, enteric-coated, prolonged action
• Diclofenac retard Obolenskoe tablets, coated, soluble in the intestine, prolonged action
• Diclofenac Sandoz extended-release tablets, enteric-coated tablets, film-coated tablets
• Diclofenac Stada rectal suppositories, enteric-coated tablets, film-coated tablets, prolonged action
• Diclofenac-AKOS ointment for external use, solution for intramuscular administration
• Diclofenac-Acri gel for external use, ointment for external use
• Diclofenac-Acri retard film-coated tablets
• Diclofenac-Altfarm rectal suppositories
• Diclofenac-MFF ointment for external use, rectal suppositories
• Diclofenac-Ratiopharm retard capsules, rectal suppositories, enteric-coated tablets
• Diclofenac-UBF enteric-coated tablets
• Diclofenac-FPO enteric-coated tablets
• DIKLOFENAC-ESCOM solution for intramuscular injection
• DIKLOFENACLONG eye drops
• Diclofenacol cream for external use
• Diphen solution for injection, enteric-coated tablets
• Dorosan aerosol for external use
• Naklof eye drops
• Naklofen gel for external use, solution for intramuscular administration, rectal suppositories, enteric-coated tablets
• Naklofen Duo Modified Release Capsules
• NAKLOFEN SR film-coated tablets
• Sodium diclofenac tablets, film-coated, soluble in the intestine
• Ortofen gel for external use, ointment for external use, solution for intramuscular administration, enteric-coated tablets
• Orthofer ointment for external use, solution for intramuscular administration, enteric-coated tablets
• ORTOFLEX ointment for external use
• RAPTEN DUO modified release tablets
• Rapten rapid film-coated tablets, sugar-coated tablets
• Revmavec solution for intramuscular administration
• Revodina retard tablets retard
• Remetan enteric-coated tablets
• Sanfinak
• SwissJet
• SwissJet Duo
• Tabuk-Dee pills
• Feloran gel for external use
• Feloran 25 enteric coated tablets
• Feloran retard tablets, enteric-coated, prolonged action
• Flotak

"Pain in the back, muscles and joints", "Diseases of the joints and spine (osteochondrosis, arthrosis, arthritis, bursitis)", "Non-steroidal anti-inflammatory drugs"

Analogues of the medicine NEURODICLOVIT in categories

"Diseases of the joints and spine (osteochondrosis, arthrosis, arthritis, bursitis)", "Non-steroidal anti-inflammatory drugs"

Analogues of the medicine NEURODICLOVIT in categories

"Pain in the back, muscles and joints", "Diseases of the joints and spine (osteochondrosis, arthrosis, arthritis, bursitis)"

Analogues of the medicine NEURODICLOVIT in categories

"Pain in the back, muscles and joints", "Non-steroidal anti-inflammatory drugs"

Analogues of the medicine NEURODICLOVIT in categories

"Non-steroidal anti-inflammatory drugs"

Analogues of the medicine NEURODICLOVIT in categories

"Diseases of the joints and spine (osteochondrosis, arthrosis, arthritis, bursitis)"

Neurodiclovitis in Moscow

Instructions

• Not found or contains natural ingredients and non-standardized active ingredients that do not belong to international non-proprietary names (INN).

NSAIDs in combination with B vitamins. Diclofenac has anti-inflammatory, analgesic, antiplatelet and antipyretic effects. By indiscriminately oppressing COX-1 and COX-2, it disrupts the metabolism of arachidonic acid, reduces the amount of prostaglandins in the focus of inflammation. In rheumatic diseases, the anti-inflammatory and analgesic effect of diclofenac contributes to a significant decrease in the severity of pain, morning stiffness, swelling of the joints, which improves the functional state of the joint. In case of injuries, in the postoperative period, diclofenac reduces pain and inflammatory edema.

Thiamin (vitamin B 1) in the human body, as a result of phosphorylation processes, it turns into cocarboxylase, which is a coenzyme of many enzymatic reactions. Vitamin B 1 plays an important role in carbohydrate, protein and fat metabolism. It actively participates in the processes of conduction of nervous excitement in synapses.

Pyridoxine (vitamin B 6) necessary for the normal functioning of the central and peripheral nervous system. In phosphorylated form, it is a coenzyme in the metabolism of amino acids (decarboxylation, transamination). Acts as a coenzyme of the most important enzymes acting in nerve tissues. It participates in the biosynthesis of many neurotransmitters such as dopamine, serotonin, norepinephrine, adrenaline, histamine and GABA.

Cyanocobalamin (vitamin B 12) is necessary for normal hematopoiesis and maturation of erythrocytes, and also participates in a number of biochemical reactions that ensure the vital activity of the body - in the transfer of methyl groups, in the synthesis of nucleic acids, protein, in the exchange of amino acids, carbohydrates, lipids. It has a beneficial effect on the processes in the nervous system (synthesis of nucleic acids and the lipid composition of cerebrosides and phospholipids). The coenzyme forms of cyanocobalamin, methylcobalamin and adenosylcobalamin, are required for cell replication and growth.

The combination of B vitamins potentiates the analgesic effect of diclofenac.

Diclofenac absorption is fast and complete. Food slows down the absorption rate by 1-4 hours and reduces C max by 40%. After oral administration of diclofenac at a dose of 50 mg, C max is achieved in 2-3 hours and is 1.4 μg / ml. Plasma concentration is linearly dependent on the dose taken. Bioavailability is 50%.

Changes in the pharmacokinetics of diclofenac against the background of repeated administration are not observed, does not cumulate. Plasma protein binding - more than 99% (most of it binds to albumin). Penetrates into synovial fluid. C max in synovial fluid is observed 2-4 hours later than in plasma. Diclofenac is excreted in breast milk. V d - 550 ml / kg.

50% of the active substance is metabolized during the "first pass" through the liver. Metabolism occurs as a result of multiple or single hydroxylation and conjugation with glucuronic acid. The isoenzyme CYP2C9 takes part in the metabolism of the drug. The pharmacological activity of metabolites is lower than that of diclofenac.

T 1/2 from the synovial fluid is 3-6 hours. The concentration of diclofenac in the synovial fluid 4-6 hours after taking the drug is higher than in the plasma, and remains higher than the plasma values ​​for another 12 hours. The relationship of the drug concentration in the synovial fluid with the clinical efficacy of the drug has not been clarified. Systemic clearance is 350 ml / min. T 1/2 from plasma - 2 hours 65% of the administered dose is excreted as metabolites by the kidneys, less than 1% is excreted unchanged, the rest of the dose is excreted as metabolites in the bile.

In patients with severe renal failure (CC<10 мл/мин) увеличивается выведение метаболитов с желчью, при этом увеличения их концентрации в крови не наблюдается.

In patients with chronic hepatitis or compensated liver cirrhosis, the pharmacokinetic parameters of diclofenac do not change.

The vitamins that make up Neurodiclovit are water-soluble, which excludes the possibility of their cumulation in the body.

Thiamine and pyridoxine are absorbed in the upper part of the small intestine, metabolized in the liver and excreted by the kidneys (about 8-10% - unchanged). The degree of absorption depends on the dose; in case of an overdose, the excretion of thiamine and pyridoxine through the intestine is significantly increased.

The absorption of cyanocobalamin depends to a large extent on the presence of an intrinsic factor in the body (in the stomach and upper part of the small intestine); further delivery of the vitamin to the tissue is determined by the transport protein transcobalamin. After metabolism in the liver, cyanocobalamin is excreted mainly in the bile, the degree of excretion by the kidneys is variable - from 6 to 30%.

Pain syndrome in inflammations of a non-rheumatic nature (after injuries, surgical and dental interventions; in gynecological diseases - primary algomenorrhea, adnexitis; in inflammatory diseases of the ENT organs - pharyngitis, tonsillitis, otitis media);

Inflammatory and degenerative diseases of the joints and spine (chronic polyarthritis, rheumatic and rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, spondyloarthrosis);

Neuritis and neuralgia (cervical syndrome, lumbago, sciatica);

Acute gouty arthritis;

Rheumatic lesions of soft tissues.

Capsules should be taken orally with meals, without chewing and drinking plenty of fluids.

For adults, Neurodiclovit is prescribed 1 capsule 3 times / day at the beginning of treatment, as a maintenance dose, once a day. The duration of therapy depends on the nature and severity of the disease.

From the digestive system:> 1% - epigastric pain, bloating, diarrhea, nausea, constipation, flatulence, increased liver enzymes, peptic ulcer with possible complications (bleeding, perforation), gastrointestinal bleeding;<1% – рвота, желтуха, мелена, появление крови в кале, поражение пищевода, афтозный стоматит, сухость слизистых оболочек (в т.ч. рта), гепатит (возможно молниеносное течение), некроз печени, цирроз, гепаторенальный синдром, изменение аппетита, панкреатит, холецистопанкреатит, колит.

From the nervous system:> 1% - headache, dizziness;<1% - нарушение сна, сонливость, депрессия, раздражительность, асептический менингит (чаще у больных системной красной волчанкой и другими системными заболеваниями соединительной ткани), судороги, общая слабость, дезориентация, кошмарные сновидения, ощущение страха.

From the senses:> 1% - tinnitus;<1% - нечеткость зрения, диплопия, нарушение вкуса, обратимое или необратимое снижение слуха, скотома.

Dermatological reactions:> 1% - itchy skin, skin rash;<1% - алопеция, крапивница, экзема, токсический дерматит, многоформная экссудативная эритема (в т.ч. синдром Стивенса-Джонсона), токсический эпидермальный некролиз (синдром Лайелла), повышенная фоточувствительность, мелкоточечные кровоизлияния, буллезные высыпания.

From the urinary system:> 1% - fluid retention;<1% – нефротический синдром, протеинурия, олигурия, гематурия, интерстициальный нефрит, папиллярный некроз, острая почечная недостаточность, азотемия.

From the hematopoietic system: <1% – анемия (в т.ч. гемолитическая и апластическая анемии), лейкопения, тромбоцитопения, эозинофилия, агранулоцитоз, тромбоцитопеническая пурпура.

From the respiratory system: <1% – кашель, бронхоспазм, отек гортани, пневмония.

On the part of the cardiovascular systems: <1% – повышение АД, застойная сердечная недостаточность, экстрасистолия, боль в грудной клетке, инфаркт миокарда.

Allergic reactions: <1% - анафилактоидные реакции, анафилактический шок (обычно развивается стремительно), отек губ и языка, аллергический васкулит.

Others: <1% – ухудшение течения инфекционных процессов (в т.ч. развитие некротического фасциита).

Erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase);

Complete or incomplete combination of bronchial asthma, recurrent polyposis of the nasal mucosa and paranasal sinuses and intolerance to acetylsalicylic acid or other NSAIDs (including history);

Hemostasis disorders (including hemophilia);

Inflammatory bowel disease;

Severe liver failure;

Active liver disease;

Severe renal failure (CC less than 30 ml / min);

Progressive kidney disease;

Severe heart failure;

The period after coronary artery bypass grafting;

Lactation period (breastfeeding);

Hypersensitivity to the components of the drug;

Hypersensitivity to other NSAIDs or vitamins.

WITH caution: peptic ulcer and duodenal ulcer, ulcerative colitis, Crohn's disease, a history of liver disease, hepatic porphyria, chronic hepatic failure, chronic heart failure, arterial hypertension, a significant decrease in BCC (including after major surgery), elderly patients (including those receiving diuretics, weakened patients and with low body weight), bronchial asthma, concomitant use of corticosteroids (including prednisolone), anticoagulants (including warfarin), antiplatelet agents (incl. acetylsalicylic acid, clopidogrel), selective serotonin reuptake inhibitors (including citalopram, fluoxetine, paroxetine, sertraline), coronary artery disease, cerebrovascular diseases, dyslipidemia / hyperlipidemia, diabetes mellitus, peripheral arterial disease / chronic renal K , the presence of Helicobacter pylori infection, prolonged use of NSAIDs, alcoholism, severe somatic diseases, smoking.

The drug is contraindicated during pregnancy and lactation (breastfeeding).

Due to the negative effect on fertility, it is not recommended to prescribe the drug to women planning to become pregnant.

In patients with infertility (including those undergoing examination), it is recommended to cancel the drug.

Symptoms: vomiting, bleeding from the gastrointestinal tract, epigastric pain, diarrhea, dizziness, tinnitus, lethargy, convulsions; rarely - increased blood pressure, acute renal failure, hepatotoxic effect, respiratory depression, coma.

Treatment: gastric lavage, activated charcoal, symptomatic therapy aimed at eliminating an increase in blood pressure, impaired renal function, seizures, irritation of the gastrointestinal tract, respiratory depression. Forced diuresis, hemodialysis are ineffective (due to significant binding to plasma proteins and intensive metabolism).

With the simultaneous use of Neurodiclovit increases the plasma concentration of digoxin, methotrexate, lithium preparations and cyclosporine.

With the simultaneous use of Neurodiclovit reduces the effect of diuretics, against the background of potassium-sparing diuretics, the risk of hyperkalemia increases.

With the simultaneous use of Neurodiclovit and anticoagulants, thrombolytic agents (alteplase, streptokinase, urokinase), the risk of bleeding (more often gastrointestinal bleeding) increases.

With the simultaneous use of Neurodiclovit reduces the effects of antihypertensive and hypnotics.

With the simultaneous use of Neurodiclovit increases the likelihood of side effects of other NSAIDs and GCS (gastrointestinal bleeding), the toxicity of methotrexate and the nephrotoxicity of cyclosporine.

Acetylsalicylic acid reduces the concentration of diclofenac in the blood.

The simultaneous use of Neurodiclovit with paracetamol increases the risk of developing the nephrotoxic effects of diclofenac.

With the simultaneous use of Neurodiclovit reduces the effect of hypoglycemic agents.

When used simultaneously with Neurodiclovitis, cefamandol, cefoperazone, cefotetan, valproic acid and plikamycin increase the incidence of hypoprothrombinemia.

Cyclosporine and gold preparations increase the effect of diclofenac on the synthesis of prostaglandins in the kidneys, which increases the risk of nephrotoxicity.

The simultaneous appointment of Neurodiclovit with ethanol, colchicine, corticotropin, serotonin reuptake inhibitors and St. John's wort increases the risk of gastrointestinal bleeding.

Diclofenac enhances the effect of drugs that cause photosensitization.

Drugs that block tubular secretion increase the plasma concentration of diclofenac, thereby increasing its toxicity.

Neurodiclovitis reduces the antiparkinsonian efficacy of levodopa.

Ethanol dramatically reduces the absorption of thiamine (blood levels can decrease by 30%).

Long-term treatment with anticonvulsants can lead to thiamine deficiency.

The use of colchicine and biguanides reduces the absorption of cyanocobalamin.

The drug is available with a prescription.

The drug should be stored out of the reach of children, in a dry, dark place at a temperature not exceeding 25 ° C. Shelf life is 3 years.

During the period of treatment with the drug, systematic monitoring of the peripheral blood picture, liver and kidney function, and examination of feces for the presence of blood should be carried out.

To reduce the risk of developing adverse events from the gastrointestinal tract, the drug should be used in the minimum effective dose for the minimum possible short course.

In order to quickly achieve the desired therapeutic effect, the tablets are taken 30 minutes before meals. In other cases, take before, during or after meals, without chewing, drinking plenty of water.

Due to the important role of prostaglandins in maintaining renal blood flow, special care should be taken when prescribing patients with heart or renal failure, as well as when treating elderly patients receiving diuretics, and patients who, for any reason, have a decrease in BCC (including h. after extensive surgical intervention). If diclofenac is prescribed in such cases, it is recommended to monitor renal function as a precautionary measure.

If, while taking the drug, an increase in the activity of hepatic transaminases persists or increases, if there are clinical symptoms of hepatotoxicity (including nausea, fatigue, drowsiness, diarrhea, pruritus, jaundice), treatment should be discontinued.

Diclofenac (like other NSAIDs) can cause hyperkalemia.

Influence on the ability to drive vehicles and use mechanisms

During the period of treatment, a decrease in the speed of mental and motor reactions is possible, therefore, patients should refrain from driving vehicles and engaging in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.

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The site provides background information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. A specialist consultation is required!

Neurodiclovitis is a combined anti-inflammatory and anesthetic drug with B vitamins. The drug is used for the symptomatic treatment of pain in non-infectious inflammatory processes.

Composition and release forms

Currently, Neurodiclovitis is available in the form oral capsules... There are conventional capsules and capsules with modified release of active substances, but this difference is not too significant, since both varieties of the same dosage form are used according to the same rules.

Sometimes there is a mention of Neurodiclovitis injections, however, this dosage form is not on the Russian pharmaceutical market.

The composition of capsules Neurodiclovit as active ingredients includes the following substances:

• Diclofenac - 50 mg;
• Thiamine hydrochloride (vitamin B 1) - 50 mg;
• Pyridoxine hydrochloride (vitamin B 6) - 50 mg;
• Cyanocobalamin (vitamin B 12) - 250 mcg.

As auxiliary components Neurodiclovitis contains the following substances:

• Titanium dioxide;
• Gelatin;
• Iron oxide red;
• Iron oxide yellow;
• Copolymer of methacrylic acid and ethyl acrylate (Eudragit NE30D);
• Silicone antifoam SE2 MC;
• Talc;
• Triethyl acetate.

Neurodiclovit capsules have a gelatinous shell, the body of which is painted pink-yellow, and the lid is brown. The capsules contain a mixture of white granules (diclofenac) and pink powder (B vitamins) inside. The capsules are available in packs of 30.

From what the drug Neurodiclovit (therapeutic effect)

Neurodiclovit contains diclofenac and B vitamins as active ingredients. Diclofenac belongs to the group of NSAIDs - non-steroidal anti-inflammatory drugs and, accordingly, has anti-inflammatory, analgesic, antipyretic and antiplatelet effects.

Anti-inflammatory action consists in stopping the inflammatory process, reducing its severity and limiting the volume of tissues involved in inflammation. That is, diclofenac suppresses both inflammation itself and reduces its size in various organs and tissues.

Anesthetic action consists in the relief of pain syndrome caused by the inflammatory process in various tissues and organs.

Antipyretic action diclofenac is to reduce fever.

Antiplatelet action is to prevent platelets from sticking together, which improves blood flow and reduces the risk of blood clots.

All these effects of diclofenac are provided by its ability to stop the work of cyclooxygenase (COX), an enzyme that produces biologically active substances called prostaglandins. Namely, prostaglandins ensure the development and maintenance of the inflammatory process in any tissue or organ, regardless of the cause that caused it. Therefore, blocking COX stops the production of prostaglandins, as a result of which the inflammatory process cannot be maintained and quite naturally fades away, and the area of ​​the affected tissues decreases.

Diclofenac in rheumatic diseases reduces the severity of inflammation, relieves pain, eliminates morning stiffness and swelling of the joints, which significantly improves the condition and functioning of the affected joints. In case of injuries, as well as after operations, diclofenac relieves pain and relieves swelling.

Vitamin B 1 (thiamine) takes part in the metabolism, and is also necessary for the transmission of nerve impulses.

Vitamin B 6 (pyridoxine) ensures the normal functioning of the peripheral and central nervous system, since it is involved in the production of biologically active substances - neurotransmitters, such as dopamine, serotonin, norepinephrine, adrenaline, histamine and GABA. These neurotransmitters ensure the normal course of various processes in the nervous tissue, including maintaining a balanced psychological state, emotional stability, etc.

Vitamin B 12 (cyanocobalamin) ensures the formation of red blood cells in the bone marrow, and also takes part in the formation of DNA and proteins and in the metabolism of amino acids, carbohydrates and fats. In addition, cyanocobalamin has a beneficial effect on the state of the central nervous system, ensuring the stability of the membranes of nerve cells, as well as stimulating their renewal.

With regard to the combined drug Neurodiclovit, we can say that B vitamins enhance the effects of diclofenac... In addition, the presence of B vitamins provides the effects of diclofenac in relation to the nervous tissue, that is, the drug is able to stop pain in neuritis, neuralgia, etc.

Indications for use

Neurodiclovitis is indicated for use in symptomatic therapy for the following conditions or diseases:

1. Relief of pain syndrome in inflammatory diseases of various organs of a non-rheumatic nature (not joints):

• Post-injury period;
• The period after surgery;
• The period after dental interventions (for example, tooth extraction, cleaning of gum pockets, etc.);
• Gynecological diseases of a non-infectious nature, for example, pain during menstruation, adnexitis, etc.;
• Inflammatory diseases of the ENT organs - pharyngitis, tonsillitis, otitis media, sinusitis, etc.

2. Reducing the severity and volume of inflammation, as well as relieving pain in inflammatory and degenerative diseases of the joints and spine:

• Chronic polyarthritis;
• Rheumatic arthritis;
• Rheumatoid arthritis;
• Ankylosing spondylitis;
• Spondyloarthrosis;
• Acute gouty arthritis.

3. Relief of pain and inflammation in the following diseases of the nervous system:

• Cervical syndrome;
• Lumbago;

4. Rheumatic lesions of soft tissues (muscles, connective tissue, etc.).

Neurodiclovitis - instructions for use

General Provisions

Neurodiclovit capsules must be taken orally during meals, swallowing whole, without chewing, not biting or opening, but washed down with plenty of still water (at least a glass). If you need to get a quick therapeutic effect, then the capsules should be taken not during, but half an hour before meals.

Neurodiclovitis is recommended to take one capsule 1 to 3 times a day. At the initial stages of therapy, it is optimal to take 1 capsule 3 times a day, and when the desired result is achieved - relief of pain and inflammation, they switch to taking Neurodiclovit in a maintenance dosage of 1 capsule 1 to 2 times a day. The duration of the main stage of therapy is determined by the rate of disappearance of symptoms of inflammation and pain. Taking the drug in a maintenance dosage can be carried out for a long time, for several weeks in a row, in order to ensure a stable therapeutic effect.

Pregnancy and breastfeeding

The drug is contraindicated for use throughout pregnancy and breastfeeding. If a woman who is breastfeeding a baby needs to take Neurodiclovitis for any reason, then the baby should be transferred to artificial formula, refusing to breastfeed.

Since Neurodiclovit adversely affects fertility, the drug is not recommended for women planning a pregnancy.

Women undergoing examination or treatment for infertility are also advised to stop taking Neurodiclovitis.

special instructions

During the entire period of therapy with Neurodiclovitis, one should systematically monitor the blood picture (complete blood count with leukoformula), liver and kidney function, and also examine feces for the presence of occult blood.

If, while taking Neurodiclovit, the activity of transaminases (ASAT, ALAT) increases or symptoms of liver damage appear, such as nausea, fatigue, drowsiness, diarrhea, pruritus, jaundice, then you should discontinue the drug and consult a doctor.

In order to reduce the risk of side effects from the digestive tract, it is recommended to take Neurodiclovit in a minimum dosage, minimizing the duration of the course of therapy.

Especially closely monitor renal function when using Neurodiclovit in people suffering from renal or heart failure, as well as in elderly patients (over 65 years old) taking diuretics. In addition, kidney function must be monitored with a decrease in circulating blood volume, which can occur when taking diuretics, after surgery, vomiting, diarrhea and other situations associated with the loss of fluid in the body.

Neurodiclovitis can provoke the development of hyperkalemia (the level of potassium in the blood is higher than normal).

Influence on the ability to control mechanisms

Neurodiclovitis negatively affects the ability to control mechanisms, reducing the speed of psychomotor reactions. Therefore, while taking the drug, you should abandon any activities that require a high speed of reactions and concentration.

Overdose

An overdose with Neurodiclovitis is possible and manifests itself in the following symptoms:

• Vomit;
• Lethargy;
• Increased blood pressure;
• Respiratory depression;
• Clouding of consciousness;

In children, the following symptoms may additionally occur with an overdose of Neurodiclovitis:

• Myoclonic convulsions;
• Nausea;
• Bleeding from the organs of the gastrointestinal tract;
• Dysfunction of the liver and kidneys (including liver or kidney failure).

To treat an overdose, you should first flush the stomach, then take a sorbent (for example, activated carbon, Polysorb, Polyphepan, Filtrum, Lactofiltrum, etc.). After that, drink plenty of fluids and diuretics (Furosemide) to ensure the fastest elimination of the drug from the body. If necessary, symptomatic therapy is carried out, aimed at maintaining the normal functioning of vital organs.

In case of an overdose with Neurodiclovitis, hemodialysis should not be performed, since this manipulation does not accelerate the elimination of the drug from the body.

Interaction with other drugs

Neurodiclovitis increases the concentration in the blood of Digoxin, Methotrexate, Cyclosporin and lithium preparations, therefore, the dosage of the latter may need to be reduced.

Neurodiclovitis weakens the effect of Levodopa, diuretics, hypotensive (lowering blood pressure), hypoglycemic (lowering blood glucose) and hypnotics.

With the simultaneous use of Neurodiclovit with potassium-sparing diuretics (for example, Veroshpiron, Triamteren, Spironolactone, etc.), the risk of developing hyperkalemia (increased level of potassium in the blood) increases.

When using Neurodiclovit with anticoagulants (Warfarin, Dikumarin, etc.), thrombolytics (Streptokinase, Urokinase, Alteplase, etc.), ethanol, Colchicine, Corticotropin, St. Xanax, Citalopram, Dapoxetine, etc.) increases the risk of gastrointestinal bleeding.

Taking Neurodiclovit with drugs of the NSAID group (Ibuprofen, Nimesulide, Aspirin, Nurofen, Ketorol, etc.) and glucocorticosteroids (Betamethasone, Prednisolone, Dexamethasone, etc.) increases the likelihood of side effects of these drugs.

Neurodiclovitis increases the toxicity of Methotrexate and Cyclosporin. And Paracetamol, Cyclosporin and gold preparations increase the toxic effect of Neurodiclovit on the kidneys.

Aspirin and other drugs containing acetylsalicylic acid reduce the concentration of diclofenac in the blood.

The incidence of hypoprothrombinemia (the level of prothrombin in the blood is below normal) increases when Neurodiclovit is taken simultaneously with Cefamandol, Cefoperazone, Cefotetan, Plikamycin and valproic acid.

Neurodiclovitis enhances the effect of drugs that provoke photosensitization.

Ethanol and anticonvulsants (Konvulex, Lamotrigine, valproate, etc.) impair the absorption of vitamin B 1, and colchicine and biguanides (Metformin, Fetformin, etc.) impair the absorption of vitamin B 12.

Neurodiclovitis and alcohol

Alcohol enhances the inhibitory effect of Neurodiclovitis on the central nervous system, therefore, it is not recommended to combine the medication with the use of alcoholic beverages. In addition, thanks to Neurodiclovitis, alcohol can penetrate into the brain tissue faster and in large quantities, respectively, causing damage to more neurons, which has a very negative effect on the general condition and functional activity of the brain tissue. This factor also speaks in favor of the need to refuse alcoholic beverages while taking Neurodiclovitis.

Side effects

Neurodiclovitis can provoke the following side effects from various organs and systems:

1. From the gastrointestinal tract:

• Stomach ache;
• Feeling bloated;
• Diarrhea or constipation;
• Nausea;
• Flatulence (increased gas production in the intestines);
• Increased activity of liver enzymes (AST, ALT, ALP, etc.);
• Peptic stomach ulcer with risk of bleeding or perforation;
• Gastrointestinal bleeding;
• Vomit;
• Jaundice;
• Melena (black feces);
• Damage to the tissues of the esophagus;
• Aphthous stomatitis;
• Hepatorenal syndrome;
• Change in appetite;
• Cholecystopancreatitis;
• Colitis.

2. From the nervous system:

• Headache;
• Dizziness;
• Sleep disturbance;
• Drowsiness;
• Aseptic meningitis (usually in people with systemic lupus erythematosus or other connective tissue diseases);
• General weakness;
• Disorientation;
• Nightmares;
• Fears.

3. From the senses:

• Noise in ears;
• Blurred vision;
• Diplopia (double vision);
• Disturbance of taste;
• Hearing impairment, which may be reversible or irreversible;
• Scotoma.

4. On the part of the skin and soft tissues:

• Itchy skin;
• Skin rash ;
• Alopecia (baldness);
• Toxic dermatitis;
• Exudative erythema multiforme (Stevens-Johnson syndrome);
• Toxic epidermal necrolysis (Lyell's syndrome);
• Photosensitivity;
• Pinpoint hemorrhages.

5. From the genitourinary system:

• Fluid retention in the body;
• Nephrotic syndrome;
• Proteinuria (protein in the urine);
• Oliguria (decrease in the amount of urine excreted);
• Hematuria (blood in the urine)
• Interstitial nephritis;
• Papillary necrosis;
• Acute renal failure
• Azotemia (the level of residual nitrogen in the blood is higher than normal);
• Decreased libido.

6. Blood system:

• Anemia;
• Leukopenia (the total number of blood leukocytes is below normal);
• Thrombocytopenia (the total number of platelets in the blood is below normal);
• Eosinophilia (the number of eosinophils in the blood is higher than normal);
• Agranulocytosis (absence of neutrophils, basophils and eosinophils in the blood);
• Aggravation of the course of chronic infectious diseases.

7. From the respiratory system:

• Bronchospasm;
• Laryngeal edema;
• Pneumonitis.

8. On the part of the cardiovascular system:

• Enhancement

Forbidden during pregnancy

Forbidden while breastfeeding

Forbidden to children

Has restrictions for seniors

Has limitations for liver problems

Has limitations for kidney problems

The combined Austrian drug Neurodiclovit, which is manufactured by Gerot Lannach Pharma, belongs to the group of non-selective NSAIDs, it combines high efficiency with relative safety of use. The neurotropic B vitamins included in its composition normalize the functioning of the nervous system, have an analgesic effect, enhance the effect of the main substance, as a result of which a lower dosage is used for treatment.

The drug is produced in the form of capsules with modified release of active substances. The composition of Neurodiclovit includes the following components:

• diclofenac sodium - 50 mg;
• thiamine hydrochloride, vitamin B1 - 50 mg;
• pyridoxine hydrochloride, vitamin B6 - 50 mg;
• cyanocobalamin, vitamin B12 - 0.25 mg.

Neurodiclovitis is indicated for the following pathologies:

• chronic joint diseases with pain syndrome (polyarthritis, gouty arthritis, etc.);
• back pain caused by neuritis and neuralgia;
• spondyloarthritis;
• osteocondritis of the spine;
• ankylosing spondylitis;
• pain syndromes in gynecology and dentistry;
• extra-articular rheumatism;
• post-traumatic inflammatory processes;
• swelling with pain syndrome;
• lumbago;
• sciatica.

Analogs and substitutes for Neurodiclovitis do not contain the entire complex of active and auxiliary substances and have a narrower therapeutic focus, thereby their cost is much lower.

Prices for the drug and its main analogues, average in Russia

Many analogues of Neurodiclovit capsules have recently appeared on the pharmaceutical market, their prices fluctuate both in different regions and in various pharmacy chains, but on average, analogues can be purchased 2 or more times cheaper.

Among them, analogs are most often offered in terms of partial composition and similar therapeutic effect, such as tablets Ketorlac, Diclofenac, Bol-Ran, Ketorol, Diklaka, Diclokain, Ketanov, Aertala, Diklovit, Doloxen, Fanigan, Ortofen, Flamidez, Voltaren; capsules Naklofen Duo and others.

N p / p	Drug name	Release form	Volume	Price
1.	Neurodiclovitis	Capsule 30 pcs.	75 mg	1250
2.	Aertal	Tablets 20 pcs.	0.1 g	383
3.	Voltaren	Tablets 20 pcs.	50 mg	298
4.	Diklak	Tablets 10 pcs.	75 mg	73
5.	Diklovit	Rectal suppositories	50 mg	156
6.	Diclofenac	Tablets 20 pcs.	50 mg	46
7.	Ketanov	Tablets 100 pcs.	10 mg	195
8.	Ketorol	Tablets 20 pcs.	10 mg	37
9.	Ketorolac	Tablets 20 pcs.	10 mg	39
10.	Tablets 20 pcs.	25 mg	50

In each specific case of the disease, the doctor can pick up several analogues of Neurodiclovitis to relieve pain syndromes and alleviate the patient's condition in various price groups.

Characteristics of common analogs based on diclofenac

Analogues of Neurodiclovit with the same complex composition of vitamins and NSAIDs are not produced. Substitutes with diclofenac cover only a certain part of the therapeutic indications, so it is important to choose the right drug from a wide drug group that is the most effective and suitable in composition.

Blockium B12

Produced in Argentina by the Casasco Laboratory A.P.T.T. the analogue of Neurodiclovit is not a complete analogue of the drug, it contains only one vitamin of group B. It belongs to non-steroidal anti-inflammatory and antirheumatic drugs that affect the human musculoskeletal system. It includes:

• diclofenac potassium;
• betamethasone;
• cyanocobalamin, vitamin B12.

Blokium B12 tablets are effective for quickly relieving pain and swelling of various etiologies:

• traumatic (after fractures, sprains, bruises, surgery);
• gynecological (with dysmenorrhea, menstruation, adnexitis);
• rheumatic and neurological;
• colds and ENT diseases.

The drug is available in tablet form. Contraindicated in children under 14 years of age, with allergies to components, intolerance to nonsteroidal drugs, duodenal and stomach ulcers, renal failure, diseases of the cardiovascular system, diabetes mellitus, osteoporosis, in the second half of pregnancy and lactation.

A combined anesthetic, antipyretic and anti-inflammatory drug of Indian origin. Contains 50 mg of diclofenac and 500 mg of paracetamol. Effectively reduces pain and high temperature, eliminates joint stiffness during movement, relieves inflammation. Has a short half-life of the constituents from the body.

It is administered orally, daily doses should not exceed 4 tablets, the optimal period of administration is 5 days. It can cause side effects such as sensory disturbances, seizures, headaches, sleep disturbances and even loss of consciousness.

In addition, stomach pains, nausea and vomiting, flatulence, and sometimes gastrointestinal bleeding may appear. Excessive doses or prolonged use can also cause anemia, edema, provoke a hypertensive crisis, bronchospasm, acute renal failure

The drug is contraindicated in children under 14 years of age, people with hypersensitivity to paracetamol and diclofenac, patients with peptic ulcers or impaired kidney and liver function. During the period of taking the drug, it is better to refuse to drive a car or work that requires special care and caution. Treatment of pregnant and lactating women with this drug is strictly prohibited.

Diklak

The German drug (Salyutas Pharma GmbH) belongs to the group of antirheumatic, anti-inflammatory, decongestant and analgesic drugs, it has only one active substance - diclofenac as a derivative of phenylacetic acid.

Available in the form of enteric tablets 50 mg, modified release tablets (75 mg, 150 mg) or solution for injection in ampoules of 3 and 25 mg. The effect of the drug is manifested on average 2-3 hours after taking the pill and after 10-20 minutes in the case of intramuscular administration.

There is significant relief after 1-2 weeks of using the therapeutic agent in patients with diseases:

• gout;
• rheumatoid arthritis;
• tendinitis;
• periarthritis;
• bursitis;
• joint injuries;
• postoperative pain.

The drug has the same side effects and contraindications as the main group of non-steroidal anti-inflammatory and antirheumatoid drugs.

Diclokain

Produced in Ukraine by the pharmaceutical company "Health". In addition to diclofenac, it contains lidocaine hydrochloride. Available only in 2 ml ampoules for injection. It has analgesic, anti-inflammatory and antipyretic effects. The presence of lidocaine significantly reduces pain symptoms at the injection site. It is absorbed by intramuscular administration within 10-20 minutes.

It is prescribed strictly according to the prescription for such diseases:

• exacerbation of rheumatism;
• various types of neuralgia;
• arthritis of various origins;
• hepatic and renal colic;
• thrombophlebitis and other diseases accompanied by pain and fever.

Diclokaine relieves pain within 3-5 days, without causing serious side effects, except for individual intolerance to the components of the drug. The drug is contraindicated in children and the elderly. Other contraindications for use include:

• peptic ulcer;
• pregnancy and breastfeeding;
• asthma;
• blood diseases;
• heart and renal failure.

Diclofenac

Non-steroidal anti-inflammatory drug, manufactured by Hemofarm AD, Serbia-Russia. The composition contains one active ingredient - diclofenac. It is used to relieve pain in the following branches of medicine:

• surgery;
• gynecology;
• oncology;
• neurology;
• sports medicine;
• traumatology;
• urology;
• ophthalmology.

The medication is presented in two variations:

1. Enteric-coated tablets, 50 mg;
2. Tablets with prolonged action in a film shell of 100 mg.

Treatment with the drug is carried out for a limited time. It has been established that long-term administration of the drug can cause cardiovascular diseases, up to heart attacks. There are also abnormalities in the nervous system (drowsiness, dizziness, memory loss, disorientation, mental disorders, etc.). The drug also affects the state of the sense organs. There may be a deterioration in vision, hearing, and taste impairment.

Dolex

Produced in India by Twilight Litaka Pharma Limited, it belongs to the NSAID group, contains two active substances: paracetamol - 500 mg and diclofenac - 50 mg. Two-layer tablets: white part and orange with splashes. Pharmacological action combines the features of each of the active ingredients included in the composition. Diclofenac promotes:

• restoration of joint mobility;
• abatement of pain;
• inhibition of platelet aggregation.

Paracetamol relieves:

• inflammation;
• pain symptoms.

In addition to the typical indications for the use of such analogs, diclofenac is effective for severe migraines, inflammatory diseases of the ears, throat and nose with severe severe pain. The drug is not advised to be used longer than 5-7 days, after which the side effects typical for this drug group intensify.

In addition, there have been cases of erosions and ulcers in the gastrointestinal tract, hemorrhagic colitis, bronchospasm, tachycardia, arterial hypertension, anemia, pancreatitis and pneumonia.

The combined preparation of the NSAID group contains active ingredients per 1 tablet:

• paracetamol - 500 mg;
• diclofenac potassium - 50 mg;
• serratiopeptidase - 15 mg.

The authors of the combination from the Indian company J. Duncan Healthcare Pvt. Ltd. have selected just such a proportion of components to enhance the action of an antipyretic-analgesic with a proteolytic enzyme. Therefore, the drug is effective in combating inflammation, accompanied not only by severe pain, but also by significant swelling and fever.

Maxigezik is used to quickly relieve acute pain in diseases of the musculoskeletal system, muscle and neuralgic disorders, toothache and in genicology. It has the same dosage, timing of use, side effects and contraindications as other NSAID analogues. Fanigan, Diklovit and Tilda are complete analogues in terms of the composition of active ingredients.

Naklofen Duo

A drug with one active ingredient - sodium diclofenac. Produced in Slovenia by the international pharmaceutical company "Krka", specializing in generic drugs. Presented in the form of modified release capsules.

1 capsule 75 mg contains the same substance in two forms:

• 25 mg enteric diclofenac;
• 50 mg of a substance with a prolonged action.

This provides an increase in the duration of the therapeutic effect and reduces the intake of the drug. The daily dose is not more than 150 mg, the course is 1-2 weeks. Indications for use, side effects and contraindications are the same as for analogues.

A negative effect of the medicinal product on fertility has been noted, in this regard, the drug is not prescribed to women who are planning pregnancy. Naklofen Duo is contraindicated in patients with alcoholism.

It should be borne in mind that in case of infectious diseases, the drug masks their symptoms.

When using the drug, it is impossible to perform work with a high degree of risk, since the speed of the physical and mental reaction decreases.

Ukrainian non-steroidal drug with analgesic and anti-inflammatory effects. Available in several forms:

• pills;
• gel;
• ointment;
• injection solution.

The composition includes diclofenac sodium as a base substance. Auxiliary components are selected in accordance with the form of release. Ortofen is indicated in the treatment of inflammatory processes accompanied by severe pain:

Contraindications and side effects are the same as for other similar drugs in this group.

Fanigan

Non-steroidal drug from the Indian-Ukrainian manufacturer Kusum Helthker Pvt. Ltd / Kusum Pharm for the relief of inflammation, fever and pain. Made on the basis of paracetamol and diclofenac. The active substances inhibit prostaglandins, which are present in all human tissues and organs, and increase sensitivity to pain mediators.

It is produced in tablets with prolonged action, which contain 50 mg of sodium diclofenac and 500 mg of paracetamol. It is indicated for the treatment of fevers, inflammation and pain caused by the following conditions:

• arthritis;
• spondylitis;
• gynecological and dental diseases;
• orthopedic edema and trauma.

The combination of active ingredients prevents joint degeneration, restores their motor activity, and normalizes thermoregulation. The drug has a number of contraindications:

• children up to age 14;
• intolerance to the main components;
• stomach ulcer;
• proctitis and hemorrhoids;
• internal bleeding;
• problems with the functioning of the kidneys, liver and cardiovascular system;
• congenital hyperbilirubinemia;
• planning pregnancy, gestational period, breastfeeding.

It is often used at bedtime to relieve pain symptoms during the patient's rest and recovery period.

The dosage does not exceed 3 tablets per day, treatment is 3-7 days. For the elderly, the dose should be reduced.

Flotak

Novartis Pharma AG (Switzerland) produces capsules containing 75 mg of long-acting diclofenac sodium. Dosage, indications for use, symptoms of overdose, restrictions and prohibitions on taking the medicinal product are similar to those common for the treatment group. Studies also note the effectiveness of drug therapy in such cases:

• surgical and post-traumatic treatment in ophthalmology;
• migraines of various nature;
• inflammation caused by internal prosthetic devices (implant or graft);
• inflammatory processes in the small pelvis.

Performing antipyretic function, the drug at the same time is not indicated for use in isolated fever. Unlike other analogues, Flotak is well tolerated by children over 6 years old.

Ketorolac based substitutes

Among the non-steroidal drugs aimed at relieving inflammation and developed on the basis of acetic acid derivatives, one can single out funds with ketorolac. The action of this substance is as close as possible to diclofenac.

Ketanov

An effective non-narcotic analgesic manufactured by the Indian company Ranbaxi Laboratories Limited. It is used to relieve pain syndromes of moderate to severe severity of various origins. It also has anti-inflammatory properties and moderately lowers fever, while it does not depress respiration, does not affect receptors, does not cause dependence and sedative action, in terms of the effectiveness of pain relief it is comparable to morphine. It is used once and in treatment courses for 5-7 days.

As an active substance, in contrast to Neurodiclovit, this preparation uses another derivative of acetic acid, which also belongs to the group of non-steroidal anti-inflammatory drugs, ketorolac tromethamine.

Available in two forms:

1. Tablets (10 mg) with the characteristic “KVT” logo engraved on one side.
2. A solution for intramuscular injection of a weakly pronounced yellowish color (ampoules of 1 ml).

The use is contraindicated in the following cases:

• hypersensitivity to components;
• asthmatic manifestations;
• ulcers;
• hemophilia;
• renal and hepatic impairment;
• strokes;
• bleeding;
• the period of pregnancy and breastfeeding;
• children under 16 years old.

Ketorolac

Ketorolac is produced in Russia and Belarus in the form of tablets, as well as a solution for intramuscular and intravenous administration. The active ingredient ketorolac tromethamine helps relieve pain and inflammation, thereby lowering the temperature caused by inflammatory processes. It is especially effective in postoperative therapy.

Doses are selected in proportion to the intensity of pain manifestations in the range of 15-30 mg every 4-6 hours, the course of treatment is no more than 5 days. Overdose can lead to ulcerative lesions of the gastrointestinal tract, interruptions in the work of the kidneys, loss of consciousness.

Macrobolic-MRP is a fully balanced nutritional substitute, providing the most efficient absorption ratio of carbohydrates, proteins and fats: 45/35/20, creating an optimal anabolic environment inside your body for muscle growth and recovery and weight control. Contains three essential nutrient complexes that are the foundation for muscle growth, body fat reduction, endurance and recovery.
GLYCEMIX LGI is a unique combination of low glycemic index (GI) carbohydrates that provides energy over time, accelerates glycogen replenishment and helps control weight. This complex was specially designed to stabilize blood sugar levels and even supply glucose to working muscles.
PROBOLIC is a protein complex consisting of soy protein, whey protein concentrate and caseinate. Contains a high level of essential essential amino acids: glutamine, arginine, leucine, isoleucine, valine. This complex provides a continuous flow of amino acids into the bloodstream through a combination of "fast" and "slow" proteins, thereby maintaining an optimal anabolic environment for recovery and muscle building, as well as preventing the process of catabolism.
LIPOBOLIC is a complex of essential fatty acids obtained from sources such as borage oil, flax seeds, evening primrose oil. This complex contains medium chain triglycerides (MCTs) - an ideal source of energy - as well as CLA, which studies have shown to help reduce body fat and increase lean muscle mass.

Tastes:
chocolate, vanilla.

Properties:
optimal ratio of carbohydrates / proteins / fats: 45/35/20.
32 g of high quality Probolic® protein for muscle recovery and growth.
Slow Carb ™ complex of carbohydrates with a low glycemic index to replenish energy losses.
a complex of essential fatty acids to support a healthy metabolism and weight control.

Mode of application:
Mix the contents of one sachet with 300 ml of cold water. Take two to three servings throughout the day between meals.

Warning:
Do not use if the protective film on the package is damaged.

Composition:
GLYCEMIX LGI® low glycemic carbohydrate complex (barley and oat fiber)
PROBOLIC® protein complex (Supro®-soy protein isolate with calcium phosphate and lecithin, calcium caseinate, whey protein concentrate, leucine, isoleucine, valine)
safflower oil
sodium caseinate (from milk)
di-potassium phosphate
mono- and diglycerides
lecithin
tocopherols
natural flavor
silicon dioxide)
lipid complex:
medium chain triglycerides
essential fatty acid blend (borage seed oil (GLA) conjugated linoleic acid (CLA)
evening primrose oil (GLA)
flax seed powder (ALA)
omega-3 complex (EPA and DHA)
xanthan gum
carrageenan
potassium acesulfame
salt
vitamin complex (ascorbic acid, dl-alpha tocopherol acetate, retinol palmitate, niacinamide, calcium pantothenate, cholecalciferol, pyridoxine hydrochloride, riboflavin, thiamine mononitrate, cyanocobalamin, folic acid, biotin)
Banaba leaf extract (Lagestroemia speciosa).

Storage conditions and periods:
Store in a dry place at a temperature of 15-30 ° C.

Release form:
Packaging 20 bags of 90 g (1800 g).

Total analogues: 102. Price and availability of analogues Neurodiclovit in pharmacies. Before using any medication, you should definitely consult your doctor.

This page provides a list of analogues of Neurodiclovit are interchangeable drugs that have similar indications for use and belong to the same pharmacological group. Before you buy analogue Neurodiclovit, it is necessary to consult with a specialist regarding the replacement of the drug, study in detail, read the drug similar to it.

• Capsicam

  Capsicam effective for radiculitis, osteochondrosis (a disease of the spine associated with metabolic disorders in the intervertebral discs and bone tissue), arthritis (inflammation of the joint), neuralgia (pain spreading along the nerve), warming massage for athletes.

• Dolobene

  Gel Dolobene applies when:
  - hematomas and inflammation of soft tissues, muscles, tendons, tendon sheaths, ligaments after bruises, compressions, injuries;
  - neuralgia;
  - joint injuries with sprains or ruptures of the ligaments;
  - Shoulder-scapular periarthritis, shoulder epicondylitis ("tennis elbow"), tendinitis, tendovaginitis, bursitis;
  - arthritis, deforming osteoarthritis (with concomitant lesions of the periarticular tissues);
  - superficial thrombophlebitis, trophic ulcers against the background of chronic venous insufficiency.

• Fir oil

  Fir oil has antimicrobial, antiviral, anti-inflammatory, tonic, tonic, analgesic and sedative effect. Fir oil affects the cardiovascular and central nervous system; improves the function of the gastrointestinal tract; lowers blood pressure; stimulates the body's defenses; improves sleep; eliminates the effects of stress factors; activates the functions of the gonads and the entire endocrine system; accelerates recovery and rejuvenates the body.

• Aspirin-C

  Aspirin-C indicated for pain syndromes of low and medium intensity of various, including inflammatory, genesis (origin), in particular, headache, toothache, algomenorrhea (painful menstruation). Feverish conditions (a sharp rise in body temperature), including in acute respiratory (respiratory) infections. Thrombophlebitis (blockage of blood vessels by a blood clot). Thrombosis (formation of a blood clot in a vessel) of the retinal vessels. Cerebral circulation disorders. Cardiac ischemia.

• Migrenol

  Migrenol It is used to eliminate pain syndrome of mild to moderate severity: headache, migraine, toothache, muscle and rheumatic pain, muscle pain, painful menstruation.

  Migrenol also used for the symptomatic treatment of colds and flu to reduce fever.

• Sedalgin

  A drug Sedalgin is intended for the symptomatic treatment of pain syndrome with:
  - migraines, tension headaches;
  - inflammatory and degenerative diseases of the musculoskeletal system;
  - postoperative conditions;
  - diseases of the peripheral nervous system (radiculitis, plexitis, neuritis, neuralgia, polyneuritis, polyneuropathy);
  - dysmenorrhea.

• Traumeel S

  Homeopathic medicine Traumeel S used for the treatment of dislocations, sprains, bone fractures, swelling of soft tissues after operations and injuries; inflammatory processes of various organs and tissues, especially the musculoskeletal system (tendovaginitis, bursitis, styloiditis, epicondylitis, periarthritis).

• Adam's Root

  Healing balm Adam's root:
  -activates tissue regeneration,
  - has a pronounced distracting, warming effect,
  - normalizes mineral and carbohydrate metabolism in tissues,
  -activates the activity of skin receptors,
  - restores the energy balance of cells.

• Antral

  Antral used to treat both adults and children with acute and chronic hepatitis of various origins (drug, viral, toxic, alcoholic), liver cirrhosis and fatty degeneration; with inflammatory diseases of the pancreas, gallbladder, spleen; resection of the gallbladder. In order to prevent liver diseases caused by the negative effects of toxins of various etiologies: chemotherapy, radiation therapy, alimentary toxins, drugs.
  

• Panadol baby candles

  Panadol baby candles used in children from 3 to 6 years old (with a body weight of 13 to 20 kg) as an antipyretic agent: colds, flu, childhood infectious diseases (chicken pox, rubella, whooping cough, measles, scarlet fever and mumps (mumps), after vaccination, as an anesthetic: teething, toothache, ear pain with otitis media, sore throat.
  Children's Panadol suppositories are indicated for children who have difficulty taking pills or who are prone to vomiting.
  

• Nurofen syrup for children

  Nurofen indicated for children from 3 months to 12 years old: as an antipyretic agent - acute respiratory infections, acute respiratory viral infections, influenza, other infectious and inflammatory diseases, accompanied by an increase in body temperature; post-vaccination reactions; as a pain reliever - pain syndrome of mild or moderate intensity (including headache and toothache, migraine, neuralgia, pain in the ears and throat, pain with sprains), etc.
  

• Buprenorphine

  Buprenorphine are: pain syndrome (strong and moderate intensity): in cancer patients, postoperative pain, angina pectoris, myocardial infarction, renal colic, burns.
  

• Butorphanol

  Indications for the use of the drug Butorphanol are: pain syndrome of various origins (medium and strong intensity); premedication before general anesthesia; as a component for intravenous general anesthesia; pain relief during childbirth.
  

• Paracetamol

  Indications for the use of the drug Paracetamol are: pain syndrome of weak and moderate intensity of various origins (including headache, migraine, toothache, neuralgia, myalgia, algodismenorrhea; pain with injuries, burns). Increased body temperature with colds and other infectious and inflammatory diseases.
  

• Ibuprom

  Indications for the use of the drug Ibuprom are: pain of low and medium intensity of various origins (headache, toothache, painful menstruation, pain in the lower back, muscle pain, pain in rheumatic lesions of bones and joints). Fever.
  

• Viburcol

• Dolaren

  Indications for the use of the drug Dolaren are: short-term therapy of pain syndrome in rheumatic diseases (rheumatoid arthritis, osteoarthritis). Neuralgia, myalgia, lumboishalgia, post-traumatic pain syndrome accompanied by inflammation, postoperative pain, headache, migraine, algomenorrhea, adnexitis, proctitis, toothache.
  As part of the complex therapy of infectious and inflammatory diseases of the ear, throat, nose with severe pain and febrile syndrome (pharyngitis, tonsillitis, otitis media).
  

• Rapten duo

  A drug Rapten duo used for the short-term treatment of pain syndrome accompanying the following conditions:
  Symptomatic treatment of diseases of the musculoskeletal system (including rheumatoid arthritis, psoriatic arthritis, juvenile chronic arthritis, ankylosing spondylitis (ankylosing spondylitis); gouty arthritis, osteoarthritis of the peripheral joints and spine, including those with radicular syndrome, tendovaginitis;
  Pain syndrome: pain and inflammatory conditions in gynecology: algomenorrhea (painful menstruation), adnexitis (inflammation of the uterine appendages), post-traumatic and postoperative pain syndrome accompanied by inflammation, pain in cancer, headache, migraine, toothache; neuralgia, myalgia, lumbago, sciatica, ossalgia;
  As part of the complex therapy of infectious and inflammatory diseases of the ear, throat, nose with severe pain syndrome (pharyngitis, tonsillitis, otitis media).
  

• Tsefekon N

  Tsefekon N used as an anesthetic for mild and moderate pain syndrome: neuralgia, myalgia, sciatica, lumbago; degenerative-dystrophic diseases of the musculoskeletal system (osteochondrosis, osteoarthritis, ankylosing spondylitis); headache and toothache, migraine; primary algomenorrhea; as an antipyretic agent: febrile syndrome with colds, infectious, inflammatory diseases.
  

• Acelysin

  Indications for the use of the drug Acelysin are: pain of various origins: headache, ear and toothache, myalgia, neuralgia, arthralgia, pain in the postoperative period, as an antipyretic agent for febrile conditions of various etiologies, as an antiaggregatory agent for the prevention of thrombosis in cardiology and neurology, as well as for the prevention of microcirculation disorders ...
  

• Daleron S Junior

  Daleron S Junior indicated for admission in childhood as: an antipyretic agent for infectious and inflammatory (bacterial, viral) diseases, as well as after vaccination; anesthetic for acute pain (headache, toothache), muscle and joint pain in infectious and inflammatory (bacterial, viral) diseases; pain reliever for trauma, medical or dental procedures.
  

• Upsarin UPSA

  Indications for the use of the drug Upsarin UPSA are: moderate or mild pain syndrome of various origins in adults: headache (including those associated with alcohol withdrawal syndrome), toothache, migraine, neuralgia, chest radicular syndrome, myalgia and joint pain, pain during menstruation, increased body temperature colds and other infectious and inflammatory diseases (in adults and children over 15 years old).
  

• Pharmadol

  Pharmadol appoint: as an analgesic for the relief of mild or moderate pain syndrome; as an antipyretic agent for diseases of any etiology accompanied by fever; for migraine, headache, toothache, neuralgia, rheumatic diseases, arthralgia, primary dysmenorrhea.
  

• Efferalgan (children)

  A drug Efferalgan used for the treatment of children aged 1 month to 12 years, suffering from pain syndrome of mild and moderate intensity (toothache, myalgia, headache, pain during teething).
  The drug is also prescribed for the treatment of fevers of various etiologies.
  

• Askofen-P

  Askofen-P applies:
  - In adults, to relieve pain syndrome of mild and moderate intensity (headache, including migraine, toothache, muscle, joint pain, neuralgia, chest radicular syndrome, lumbago, algodismenorrhea).
  - In adults and children (over 15 years old) it can be used for "colds" and other infectious and inflammatory diseases as an antipyretic agent.
  

• Next

  Indications for the use of the drug Next are: headache (including migraine); toothache; algodismenorrhea (painful menstruation); neuralgia; myalgia; back pain; joint pain, pain syndrome in inflammatory and degenerative diseases of the musculoskeletal system; pain with bruises, sprains, dislocations, fractures; post-traumatic and postoperative pain syndrome; feverish conditions (including flu and colds).
  

• Pentalgin

  A drug Pentalgin indicated for the treatment of pain syndrome of various origins, including pain in joints, muscles, radiculitis, menstrual pain, neuralgia, toothache and headaches (including headache caused by spasm of cerebral vessels).
  Pain syndrome associated with spasm of smooth muscles, including chronic cholecystitis, gallstone disease, postcholecystectomy syndrome, renal colic.
  Post-traumatic and postoperative pain syndrome, including accompanied by inflammation.
  Colds accompanied by febrile syndrome (as symptomatic therapy).

• Analgin

  Indications for the use of the drug Analgin are:
  - Mild or moderate pain syndrome (headache, migraine, toothache, neuralgia, myalgia; dysmenorrhea; postoperative pain.
  - In combination with antispasmodics for renal and biliary colic).
  - Feverish conditions in infectious and inflammatory diseases.
  - Use as an antipyretic agent is advisable after the diagnosis of the disease.
  

• Citramon P

  Indications for the use of the drug Citramon P are:
  - Pain syndrome of mild and moderate severity (of various origins): headache; migraine; toothache; neuralgia; myalgia; arthralgia; algodismenorrhea.
  - Feverish syndrome: with acute respiratory infections; with the flu.
  

• Transtec

  Transtec used in the treatment of patients with prolonged and severe pain on the background of oncological pathologies.
  Transtek can also be used in the treatment of patients with pain syndrome that is not relieved by non-steroidal anti-inflammatory drugs (excluding acute pain syndrome).

• Pentalgin Plus

  A drug Pentalgin Plus indicated for use in moderately severe pain syndrome of various origins, including pain in joints and muscles, algodismenorrhea, neuralgia, post-traumatic pain, as well as for headaches and toothaches. Pentalgin Plus can be used as a symptomatic agent for febrile syndrome.
  

• Maxigan

  A drug Maxigan It is intended to eliminate mild or moderate pain syndrome with spasms of smooth muscles of internal organs - renal and hepatic colic, spastic pain along the intestines, algomenorrhea. It can be used for short-term symptomatic treatment for joint pain, neuralgia, sciatica, myalgia.
  As an adjuvant, it can be used to relieve pain after surgical and diagnostic interventions. If necessary, the drug can be used to reduce elevated body temperature in case of colds and infectious and inflammatory diseases.
  

• Femizol

  A drug Femizol designed to relieve symptoms of premenstrual syndrome such as bloating, weight gain due to fluid retention in the body, headaches and back pain.
  

• Nurofen Long

  Indications for the use of the drug Nurofen Long are: back pain, joint pain, muscle and rheumatic pains, neuralgia, headache, migraine, toothache, painful periods, sore throat, fever, cold and flu symptoms.
  A drug Nurofen Long especially indicated for the symptomatic treatment of pain requiring a more pronounced analgesic effect than ibuprfen or paracetamol alone.
  

• Citramarine

  Indications for the use of the drug Citramarine are:
  - Feverish syndrome: with acute flu and respiratory illness.
  - Pain syndrome of mild and moderate severity (of various origins): neuralgia; headache; migraine; algodismenorrhea; toothache; myalgia; arthralgia.
  

• Excedrin

  A drug Excedrin intended for use to eliminate pain syndrome of moderate and mild intensity of various origins: headache, migraine, toothache, neuralgia, arthralgia and myalgia (pain in muscles and joints), algomenorrhea (pain during menstruation).
  

• Nurofen Plus

  A drug Nurofen Plus is intended for short-term symptomatic treatment of pain syndrome of mild to moderate severity (headache, migraine, toothache, neuralgia, back pain, painful menstruation, muscle and rheumatic pain) with ineffective NSAID monotherapy.
  

• Naproff

  Indications for the use of the drug Naproff are: headache and toothache, migraine, menstrual pain; pain in muscles, joints and pain in the spine (disorders of the musculoskeletal system); post-traumatic pain (sprains, bruises, overexertion); postoperative pain (in traumatology, orthopedics, gynecology, surgical dentistry); rheumatic diseases (rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and gout).
  

• Aspirin Complex

  Aspirin Complex used to relieve symptoms of "colds", SARS, flu, such as: high fever and chills, headache and muscle pain, runny nose and / or nasal congestion, sore throat and sneezing.
  

• Aspirin

  A drug Aspirinit is used for the symptomatic treatment of headache, toothache; sore throat caused by a cold; algodismenorrhea; muscle and joint pain; moderate back pain due to arthritis.
  Aspirineffective for colds or acute respiratory diseases; for symptomatic relief of pain and fever.
  

• Alfort Dexa

  A drug Alfort Dexa It is used in the symptomatic treatment of acute pain of moderate to high intensity in the case when oral administration of the drug is impractical, for example, for postoperative pain, renal colic and low back pain (back pain).
  

• Pireticol

  Suspension Pireticol Recommended for pain syndrome of various origins of mild to moderate intensity, including: pain during teething, toothache, sore throat, fever with colds, flu and childhood infections such as chickenpox, whooping cough, measles, mumps (mumps) ...
  Pireticol also recommended for the treatment of post-vaccination hyperthermia in infants aged 2-3 months.
  

• Dexonal

  Musculoskeletal pain (mild or moderate), algomenorrhea, toothache.
  A drug Dexonal intended for symptomatic treatment, pain and inflammation reduction at the time of application.
  

• Artrosilene

  Indications for use capsules, suppository Artrosilene are: relief of pain of mild and moderate intensity (including pain of an inflammatory nature, postoperative and post-traumatic); rheumatic diseases: rheumatoid arthritis; spondyloarthritis; osteoarthritis; gouty arthritis; inflammatory damage to the periarticular tissues.
  Solution for i / v and i / m administration Artrosilene: short-term treatment of acute pain syndrome in diseases of the musculoskeletal system of various origins, postoperative pain, post-traumatic pain associated with inflammation.
  Gel, aerosol Artrosilene: diseases of the musculoskeletal system (including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthritis of the peripheral joints and spine, rheumatic lesions of soft tissues); muscle pains of rheumatic and non-rheumatic origin; traumatic injuries of soft tissues.
  

• Rotalfen

  Indications for the use of the drug Rotalfen are:
  - relief of pain syndrome of various origins (including postoperative pain, pain in bone metastases, post-traumatic pain, pain in renal colic, algomenorrhea, sciatica, sciatica, neuralgia, toothache);
  - symptomatic treatment of acute and chronic inflammatory, inflammatory-degenerative and metabolic diseases of the musculoskeletal system (including rheumatoid arthritis, spondyloarthritis, arthrosis, osteochondrosis).
  

• Clodifen Neuro

  Indications for the use of the drug Clodifen Neuro are:
  - pain syndrome in inflammations of a non-rheumatic nature (after injuries, surgical and dental interventions; in gynecological diseases - primary algomenorrhea, adnexitis; in inflammatory diseases of the ENT organs - pharyngitis, tonsillitis, otitis media);
  - inflammatory and degenerative diseases of the spine and joints (rheumatoid arthritis, ankylosing spondylitis - ankylosing spondylitis, spondyloarthritis, spondyloarthrosis, osteoarthritis);
  - neuritis and neuralgia (cervical syndrome, lumbago, sciatica);
  - acute gouty arthritis;
  - rheumatic diseases of the periarticular soft tissues.
  

• Ketanov

  Ketanov intended for use to eliminate pain syndrome of moderate and severe intensity of various origins (including in the postoperative period, with cancer).

• SPAZMALGON

  Spazmalgon intended for use in symptomatic treatment with mild and moderate pain syndrome with spasms of smooth muscles of internal organs:
  - renal colic and inflammatory diseases of the urinary tract, occurring with pain and dysuric disorders;
  - Spasms of the stomach and intestines, hepatic colic, biliary dyskinesia;
  - spastic dysmenorrhea.
  

• Nimesil

  Indications for the use of the drug Nimesil are: acute pain (pain in the back, lower back; pain in the musculoskeletal system, including bruises, sprains and dislocations of the joints; tendenitis, bursitis; toothache); symptomatic treatment of osteoarthritis (osteoarthritis) with pain syndrome; primary algomenorrhea.
  A drug Nimesil intended for symptomatic therapy, reducing pain and inflammation at the time of use; Nimesulide is recommended for therapy as a second-line drug.
  

• Brufica Plus

  Brufica Plus used in children from 2 years of age.
  As an antipyretic agent for: acute respiratory diseases; flu; childhood infectious diseases; post-vaccination reactions and other infectious and inflammatory diseases, accompanied by an increase in body temperature.
  As a pain reliever of mild to moderate intensity for: headache and toothache; migraine; neuralgia; pain in the ears and throat; muscle pain; pain from injuries, sprains, burns and other types of pain.
  

• Voltaren Acti

  Pill Voltaren Acti apply for:
  - Removal and reduction of pain syndrome of various origins, including: headache; toothache; pain during menstruation; muscle pain; pain in various parts of the spine.
  - Relief and reduction of symptoms of colds, flu and sore throats, including painful sensations in these conditions.
  - To reduce body temperature.
  

• Baralgin M

  A drug Baralgin M intended for use to eliminate pain syndrome of mild and moderate intensity (headache and toothache, neuralgia, pain with sciatica, osteochondrosis, arthritis, menalgia), spasms of smooth muscles (renal colic, biliary colic, intestinal colic), febrile conditions in infectious and inflammatory diseases (as part of combination therapy).
  

• Katadolon

• DIKLOBERL

• DICLOTOL

• CAVER

• NOVIGAN

• INCENA

• DOLORMIN

• VIPATOX

• PERSKINDOL

• DICLOSEIF GEL

• EMLA

• Bystrumgel

  Bysrumgel indicated for use in the following pathological conditions:
  - lesions of the lumbosacral region;
  - arthritis;
  - lumbago;
  - periarthritis;
  - tendinitis;
  - ruptures of the ligamentous apparatus;
  - muscle tears;
  - rheumatoid arthritis;
  - lymphangitis;
  - arthrosis;
  - spondyloarthritis;
  - tendosynovitis;
  - sports injuries;
  - osteochondrosis;
  - soft tissue bruises;
  - phlebitis;
  - bursitis;
  - damage to the meniscus;
  - torticollis;
  - sciatica;
  - dorsalgia;
  - dislocations;
  - myositis;
  - enthesopathy.

• Dexalgin

  Dexalgin shown as
  ... Symptomatic treatment for toothache;
  ... pain during menstruation;
  ... mild or moderate pain syndrome in diseases of the musculoskeletal system.

• Ksefokam

  Indications for the use of the drug Ksefokam are: short-term treatment of pain syndrome of various origins. Symptomatic therapy of rheumatic diseases (rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, articular syndrome with exacerbation of gout, rheumatic soft tissue damage).
  

• No-shpa

  No-shpa solution for i / v and i / m introduction: spasms of smooth muscles associated with diseases of the biliary tract (cholecystolithiasis, cholangiolithiasis, cholecystitis, pericholecystitis, cholangitis, papillitis); spasms of smooth muscles of the urinary tract (nephrolithiasis, urethrolithiasis, pyelitis, cystitis, tenesmus of the bladder); in the period of stretching during physiological childbirth, shortening the phase of cervical dilatation and thereby reducing the total duration of labor.
  As an auxiliary therapy (if oral therapy is impossible): with spasms of smooth muscles of gastrointestinal origin (gastric ulcer and duodenal ulcer, gastritis, spasms of the cardia and pylorus, enteritis, colitis); with gynecological diseases (dysmenorrhea, severe labor pains).
  No-shpa pills: spasms of smooth muscles associated with diseases of the biliary tract (cholecystolithiasis, cholangiolithiasis, cholecystitis, pericholecystitis, cholangitis, papillitis); spasms of smooth muscles of the urinary tract (nephrolithiasis, urethrolithiasis, pyelitis, cystitis, tenesmus of the bladder).
  As an auxiliary therapy: for spasms of smooth muscles of gastrointestinal origin (peptic ulcer and duodenal ulcer, gastritis, spasms of the cardia and pylorus, enteritis, colitis, spastic colitis with constipation and meteoric forms of mucous colitis);
  tension headaches; with gynecological diseases (dysmenorrhea).
  

• Paracetamol Extratab

• Dextanol

  Pills Dextanol are used to eliminate pain syndrome of mild and moderate intensity in the following diseases and conditions: acute and chronic inflammatory diseases of the musculoskeletal system (rheumatoid arthritis, spondyloarthritis, arthrosis, osteochondrosis); algodismenorrhea; toothache.
  

• Unispaz

  A drug Unispaz is intended to eliminate pain syndrome of weak and moderate intensity: (toothache and headache, pain in joints, muscles, neuralgia, sciatica, recurrent pain in women), caused, among other things, by spasms of smooth muscles (renal colic, spasms of the ureter and urinary bladder, biliary colic, intestinal colic, spastic constipation and other spastic conditions of internal organs).
  

• Saridon

  A drug Saridon It is used to relieve pain of various etiologies, including: headache, toothache, migraine pain, neuralgia, myalgia, sciatica, post-traumatic and postoperative pain, dysmenorrheal pain.
  To reduce elevated body temperature in case of colds and other infectious and inflammatory diseases.

• Sedal-M

  A drug Sedal-M It is used to eliminate mild and moderate pain syndrome of various origins: headache, toothache, migraine, pain in muscles and joints, neuralgia, with painful menstruation, with sciatica, with traumatic and postoperative pain.
  Sedal-M also used to reduce elevated body temperature in case of colds, other infectious and inflammatory diseases and influenza.
  

• Solpadein

  Solpadein used in adults and children over 12 years of age with pain syndrome (headache, toothache, migraine, pain in muscles and joints, neuralgia, painful menstruation, sciatica, sprains, sinusitis and sore throat). In adults and children over 12 years of age, to reduce elevated body temperature, with "colds", other infectious and inflammatory diseases and flu.
  

• Gofen

  A drug Gofen used in the symptomatic treatment of headache, toothache and menstrual pain; fever.
  

• Flamax

  NSAIDs for the treatment of pain.
  Flamax
  Inflammatory and degenerative diseases of the musculoskeletal system:
  - rheumatoid arthritis;
  - seronegative arthritis: ankylosing spondylitis (ankylosing spondylitis), psoriatic arthritis, reactive arthritis (Reiter's syndrome);
  - gout, pseudogout;
  - osteoarthritis.
  Pain syndrome:
  - tendinitis, bursitis, myalgia, neuralgia, sciatica;
  - migraine;
  - post-traumatic and postoperative pain syndrome;
  - pain syndrome in cancer;
  - algodismenorrhea.
  

• Ibuprofen

  A drug Ibuprofen intended for symptomatic therapy, reducing pain and inflammation at the time of use, does not affect the progression of the disease.
  - inflammatory and degenerative diseases of the musculoskeletal system: rheumatoid, juvenile chronic, psoriatic arthritis, osteoarthritis, gouty arthritis, ankylosing spondyloarthritis (ankylosing spondylitis).
  - pain syndrome: myalgia, arthralgia, ossalgia, arthritis, sciatica, migraine, headache (including with menstrual syndrome) and toothache, neuralgia, tendonitis, tendovaginitis, bursitis, post-traumatic and postoperative pain syndrome, accompanied by inflammation, in cancer diseases;
  - algodismenorrhea, an inflammatory process in the small pelvis, incl. adnexitis;
  - febrile syndrome with colds and infectious diseases.