Furazolidone for children from 3 years old. "Furazolidone" for the treatment of intestinal infections in a child: efficacy, features of administration

The body of children, especially babies up to 3-4 years old, is extremely sensitive to various infections, including intestinal infections. The developing immune system is not yet able to actively resist the introduction of pathogenic microbes - Shigella and Salmonella, Escherichia, Rotavirus, Campylobacter, which infect the digestive system and poison the child with toxins, creating a threat of the spread of the pathological process to other tissues and organs. In such situations, the drug Furazolidone comes to the rescue.

Description of the drug Furazolidone

One of the important advantages of Furazolidone is that pathogenic bacteria are not able to form drug-resistant strains, and this property determines its high efficiency.

The effectiveness of Furazolidone in killing microbes is much higher than that of Furacilin, Furadonin, Furagin, and the toxicity is about five times less.

Furazolidone tablets are allowed for children from the age of five

Furazolidone is most active against gram-positive streptococcus and staphylococcus, gram-negative bacilli Proteus, Shigella, Escherichia, Klebsiella, Enterobacter, as well as against protozoa - lamblia, Trichomonas. The pathogens of paratyphoid fever, dysentery, typhoid fever react especially strongly to the antibacterial effect of the drug.

As a result of the activity of Furazolidone, harmful microbes secrete fewer toxins, therefore, the improvement of the patient's condition often occurs very early - even before the complete suppression of the pathogenic microflora. Moreover, the drug has a rare property of stimulating the protective functions of the body and the ability of leukocytes to kill foreign microorganisms.

The drug is rapidly absorbed, excreted by the kidneys and intestines.

Forms of issue

Furazolidone is available in two pharmaceutical forms:

  • Yellow flat-cylindrical tablets with a bevel of 0.05 g. The active ingredient is furazolidone, additional substances: potato starch, lactose monohydrate, polysorbate, calcium stearate, sugar, colloidal silicon dioxide. Not used to treat children under 5 years of age.
  • Yellow and greenish-yellow granules with a characteristic odor, used in pediatrics to prepare a suspension. Packing of 50 g in glass bottles with a volume of 150 ml. Additionally, a measuring plastic cup is applied. A suspension of granules is approved for use in children from 12 months.

The concentration of the active substance in the granules is lower than in the tablets.

Indications for use

Furazolidone is effective for the following infections of the gastrointestinal system detected in a child:

Diarrhea, like vomiting, is not a disease in itself, it is an intestinal disorder, and its appearance is a sign of an underlying disease. As a rule, diarrhea accompanies any intestinal infections in babies.

And although this is only a symptom, it is diarrhea that is a common cause of death in infants and children under five years of age, since even short-term diarrhea very quickly depletes and dehydrates the child's body, removing all useful substances. Vomiting in children has the same negative property, in which dehydration occurs very quickly. Furazolidone is one of the powerful drugs that stop these manifestations, regardless of what disease caused them.

Rotavirus infection, or stomach flu, causes severe intoxication in infants and young children from six months to 2 years old with damage to the intestinal mucosa. The disease is widespread at this age due to the low acidity of gastric juice, an undeveloped immune defense system. There is no specific treatment for the infection. But treatment of the symptoms of the disease, including diarrhea and vomiting, is imperative. And in this case, Furazolidone manifests itself as one of the most effective means.

Intestinal infections in children - video by Dr. Komarovsky

How safe is Furazolidone for children?

The question of the safety of a pharmacological agent is especially important when it is used in the treatment of children. The negative effect of Furazolidone is noted very rarely, and its effectiveness in treatment is high.

Possible side effects

Adverse reactions in childhood to Furazolidone are mainly manifested at increased dosages without consulting a pediatrician while treating a child at home.

Side effects of the drug include:

  • allergic skin reactions in the form of rash like urticaria, itching;
  • nausea, vomiting, loss of appetite;
  • Quincke's edema.

Overdose

In case of an overdose or unreasonably prolonged use of the drug, the likelihood of complications in children is increased. The following pathological conditions may develop:

  1. Dangerous for infants hemolytic anemia and methemoglobinemia (an increase in the content of hemoglobin, unable to carry oxygen).
  2. Shortness of breath, fever, cough.
  3. Poisoning of liver cells (acute drug toxic hepatitis).
  4. Neurotoxic reactions (polyneuritis).
  5. Development of complications of the existing disease.

If the child has received an excessive dose of Furazolidone, an urgent call to an ambulance is required. Usually, an active one is prescribed, and in especially serious cases hemodialysis is performed - the process of purifying the blood from poisons using an "artificial kidney" apparatus.

Contraindications

Conditions for which the drug should not be taken include:

  • special sensitivity of the child to the components of Furazolidone;
  • chronic kidney failure in severe form;
  • lactase deficiency and deficiency of glucose-6-phosphate dehydrogenase (due to the content of milk sugar in Furazolidone);
  • liver disease, neurological disorders.

Interaction with other pharmacological drugs

Medicines that change the acidity (Ph) of urine are capable of accelerating the process of excretion of Furazolidone, reducing its effect (alkalizing) or, conversely, promoting the accumulation of the drug (acidifying), which increases the effect on microbes, but at the same time the likelihood of exceeding the dose and manifestations of negative reactions. Tetracycline, antibiotics of the aminoglycoside group enhance the antimicrobial properties and the therapeutic effect of Furazolidone. And the joint use with Ristomytsn and Chloramphenicol causes a sharp suppression of the functions of hematopoiesis.

Furazolidone is not used when taking ephedrine, antidepressants, phenylephrine - due to a possible sharp rise in blood pressure.

Instructions for use of the drug

Basic rules for taking Furazolidone:

  1. Give the drug to the child after meals to enhance absorption.
  2. To minimize the risk of adverse reactions during treatment with Furazolidone, children over five years of age are given a pill to drink with plenty of liquid.
  3. On the recommendation of a pediatrician, along with Furazolidone, the child should be given:
    • antihistamines, and for the prevention of neuritis - B vitamins;
    • Polysorb or activated carbon as adsorbents - substances that actively collect all the poisons in the digestive tract and remove them from the body during bowel movements.

For children under the age of five, Furazolidone is used in the form of a suspension, which is prepared from granules. Boiled water is poured into a bottle with granules to the mark on the container (100 ml of suspension is obtained) and shaken to dissolve the contents and obtain a 0.3% suspension (1 ml contains 0.0003 g of active substance).

The shaking process is carried out before each use.

The dosage is prescribed only by a doctor. It depends on the weight and age of the child, the severity of the pathological process and the type of disease, as well as the degree of sensitivity of the child's body to foods, drugs and any other allergens.

The mode of application is at least three times a day, usually 4 times after meals. PThe duration of therapy is 5-7 days, with severe infections and good tolerance - up to 10-14 days.

For the treatment of skin lesions and burns, Furazolidone is used in children at the site of the lesion using irrigation or the imposition of medical dressings soaked in a solution of the drug in the ratio indicated by the pediatric surgeon.

How can you replace the product?

If, when taking Furazolidone, a child develops an allergic reaction, or the drug is found to be ineffective, the pediatrician may prescribe another drug with a similar therapeutic effect.

Furazolidone's analogs - table

Name Release form Active substance Indications Contraindications From what age Approximate price, rub.
Furadonin Tablets 0.1 gNitrofurantoin
  • Urinary tract infections:
  • pyelitis;
  • cystitis;
  • urethritis.
  • Hypersensitivity to the drug;
  • renal and heart failure; hepatitis;
  • acute porphyria;
  • deficiency of glucose-6-phosphate dehydrogenase.
From 2 months45 – 210
Enterofuril
  • Suspension;
  • capsules.
NifuroxazideAcute or chronic infectious diarrhea.
  • Prematurity;
  • hypersensitivity to nitrofuran derivatives.
Suspension from 1 month of life, capsules from 2 years.
  • Suspension -435;
  • capsules - 385.
Stopdiar
  • Tablets;
  • suspension.
Nifuroxazide
  • Individual intolerance to the components of the drug;
  • prematurity.
Tablets from 2 years, suspension from 2 months.
  • Tablets - 265;
  • suspension - 340.
Nevigramon Capsules 500 mgNalidixic acid
  • Gastrointestinal infections;
  • cholecystitis;
  • pyelonephritis;
  • cystitis;
  • urethritis.
  • Dysfunction of the kidneys and liver;
  • epilepsy;
  • deficiency of glucose-6-phosphate dehydrogenase.
From 12 years old (with a child weighing at least 40 kg).3 890

The drug Furazolidone for children from 3 years old is prescribed by the attending physician. As you know, the baby's body at the age of 3-5 is very sensitive to most infections and diseases. Intestinal infections are no exception. A young developing organism is not yet able to withstand harmful microbes. And they, as a rule, affect the child's body, including the digestive system. This creates a threat of the spread of the pathological process to other organs. But do not despair, because Furazolidone can come to the rescue, the reception of which will help protect the child.

It should be noted that the effectiveness of Furazolidone is much higher than that of such agents as Furacilin, Furagin. As for the toxicity, Furazolidone in 50 mg tablets is about 4-5 times lower than that of other similar drugs. And since with the activity of Furazolidone in tablets, bacteria release much less toxins, the child's recovery usually occurs very early, even before the complete suppression of the pathogenic microflora. One of the possibilities of the remedy is to stimulate the protective function of the body and the ability of leukocytes to destroy harmful microorganisms.

When Furazolidone tablets are prescribed: instructions for use will tell you. Children's Furazolidone or Enterofuril in tablets of 50 mg is used for infections of the gastrointestinal tract, such as:

  • infectious food poisoning of the body;
  • salmonellosis and giardiasis;
  • cholera;
  • diarrhea and vomiting.

Diarrhea, like vomiting, is not a disease in itself, but it is considered a symptom of an intestinal disorder. The occurrence of these problems is a sign of the alleged illness of the body. It is especially worth paying attention to diarrhea, since it is she who is the precursor of other intestinal infections in the baby's body.

Parents need to know that although diarrhea is just a symptom, it is one of the main causes of death in children aged 3-4 years. After all, even the most common diarrhea can lead to exhaustion and dehydration of the child's body. And also diarrhea can remove almost all the nutrients needed to maintain life. However, not only diarrhea, but also vomiting is a very dangerous phenomenon at this age.

Furazolidone for children is exactly the medicine that is used to prevent the manifestation of the above symptoms, regardless of what disease caused them.

How to take Furazolidone

Furazolidone for children in tablets of 50 mg, like other drugs, has its own instructions for use, which must be studied before treatment.
The basic rule of thumb is:

The drug is given to the child after a meal so that it is well absorbed by the body.

In order to avoid any side effects, children are given a pill to drink with plenty of liquid.
Before using the product, you need to consult with your doctor, who can additionally select drugs that can help you get a good result much faster.

As a rule, for children from 3 years old, this agent is prescribed in the form of a suspension, which is made from granules. Yellow and green granules are used in pharmacology to make suspensions. The drug is used as follows: hot water is poured into a bottle with granules, then everything is mixed and shaken. You should get a suspension. Shake the drug before each use. The dosage should not be selected on your own. It is better to trust an experienced doctor who, based on weight, height and age data, is already prescribed the appropriate dosage. The course of treatment with the drug lasts about a week, but if the condition is severe, it can take up to 2 weeks.

Before giving a child this or that drug, parents are interested in the safety of the drug for the baby. This tool has no contraindications. But there are still some side effects, namely, allergic skin rashes on the child's body (like hives), nausea, vomiting, loss of appetite, and so on. But such side effects are very rare.

The use of Furazolidone should be abandoned in cases where the child has a special sensitivity to the components of the drug, chronic renal failure in acute form, liver disease and neurological disorders. If the baby has at least one of these symptoms, then it is better to forget about this drug so as not to worsen the situation.

If a child has contraindications to Furazolidone, then you should consult a doctor who can choose an appropriate analogue to this medicine.

Worms can live asymptomatically in your body for years and their waste products will interfere with the functioning of your body and cause other diseases, the course of which often becomes chronic.

You are familiar with the following symptoms firsthand:

  • nausea;
  • gas and bloating;
  • frequent colds;
  • poor sleep;
  • weight problems;
  • excessive nervousness;
  • fatigue;
  • skin problems?

The drug Furazolidone has proven efficacy for the treatment of infectious diseases. Compliance with the dosages indicated in the instructions for a particular disease will help reduce the risk of side effects. Before taking it, it is important to check the list of contraindications.

The composition of the drug and the form of release

The drug is presented on sale in the form of flat-cylindrical yellow tablets, which are packed in contour packs of 10 pcs (2-3 in a cardboard box) or in plastic jars of 50 pcs. The composition of Furazolidone is shown in the table:

Pharmacotherapeutic action of Furazolidone

The antimicrobial agent Furazolidone belongs to the derivatives of nitrofurans, a synthetic substance from the 5-nitrofurforol group. Gram-negative, gram-positive, aerobic bacteria (lamblia, salmonella, shigella, Trichomonas, campylobacter, cholera vibrio) are highly sensitive to it. Depending on the concentration, the drug exhibits a bacteriostatic or bactericidal effect.

The mechanism of action of Furazolidone is to block the enzyme systems of microbes. The drug disrupts cellular respiration, suppresses the Krebs cycle, and blocks the biosynthesis of nucleic acids. This leads to the destruction of the bacterial membrane, the cytoplasmic membrane. Destroyed microbial cells release less toxins and activate the immune system.

The drug does not act on anaerobic microorganisms, Pseudomonas aeruginosa, stimulates immunity, resistance to it rarely and slowly develops. The agent increases the phagocytic activity of leukocytes and the compliment titer, increases the body's sensitivity to alcohol. The drug is used to create high concentrations in the intestine for the treatment of intestinal bacterial and protozoal infections.

The tablets are poorly absorbed, but perfectly distributed in tissues and fluids (cerebrospinal fluid, plasma, intestinal lumen). The maximum concentration of the active component remains in the blood for 5.5 hours. The agent is extensively metabolized with the formation of an inactive metabolite, excreted by the kidneys, with feces.

Indications and contraindications

On the pages of the instructions, indications for the use of Furazolidone are indicated:

  • cholera;
  • dysentery;
  • paratyphoid;
  • giardiasis;
  • salmonellosis;
  • Trichomonas colpitis;
  • foodborne toxicoinfection;
  • pyelitis;
  • urethritis;
  • cystitis;
  • infected wounds, burns.

The drug is prescribed with caution in case of deficiency of glucose-6-phosphate dehydrogenase, diseases of the nervous system. Contraindications to the use of the product:

  • intolerance to the components of the composition;
  • lactation, pregnancy;
  • end stage renal failure;
  • age up to 3 years for tablets and up to a month for suspension;
  • severe liver failure.

When treating with medication, side effects are possible:

  • itching, skin rash, Quincke's edema;
  • pulmonary edema, bronchospasm;
  • decreased appetite, vomiting, nausea;
  • neuritis;
  • hepatotoxicity;
  • peripheral neuropathy (the risk is higher with anemia, diabetes mellitus, vitamin B deficiency).

An overdose of Furazolidone is manifested by toxic hepatitis, changes in the blood, polyneuritis. Treatment consists in canceling the remedy, taking antihistamines, B vitamins, drinking plenty of fluids.

Instructions for the use of Furazolidone

The drug is taken orally after meals to prevent dyspeptic disorders, washed down with water. With prolonged use for the prevention of nephritis, it is combined with vitamins of group B. Use of the drug for adults:

Disease

Dosage, g

Frequency rate of admission, once a day

Duration of treatment, days

Note

Paratyphoid fever, foodborne diseases, dysentery

Single dose 0.2 g, daily dose 0.8 g.

Giardiasis

Repeat in a week

Trichomonas urethritis

Trichomonas colpitis

Additionally, a powder based on furazolidone and lactose is injected into the vagina, into the rectum - suppositories with furazolidone 4-5 mg

Local treatment of burns

Dressings with a solution of 1: 25000

Dosage and method of administration for children

In a child, a granular form of the drug is used, from which a suspension is prepared. It is allowed from a month of life, pills - from 3 years. A single dose is 0.0025 g per kg of weight, the daily dose is 0.01 g per kg of weight, divided into 3-4 doses for a course of 5-7 days.

In infants, the drug is used to treat infected wounds and burns in the form of a sterile dressing soaked in solution. To prepare the suspension, take 100 ml of warm water, pour it into a bottle, shake and measure. When treating Furazolidone, the pediatrician must take into account the type and severity of the course of the disease, the presence of chronic ailments. General rules for the treatment of children:

  • The course lasts no longer than 10 days.
  • The tool is taken 4 times a day after meals, washed down with water.
  • In the child's diet, the amount of thiamine-containing products (canned meat and fish, smoked meats, legumes, chocolate, cheese, yogurt, kefir) is reduced - otherwise the baby will develop dizziness, high blood pressure.

Furazolidone for diarrhea

The use of Furazolidone for diarrhea helps to stop diarrhea caused by pathogenic microorganisms (shigella, amoeba, salmonella). Adults are supposed to drink 2-3 tablets 4 times a day, children over 5 years old - ½ -1 tablets the same number of times. The daily dose in children over a year old is divided into 3-4 doses and is 10 mg per kg of body weight. The effect is visible after 2-5 days of treatment, if there is no improvement after a week, the medicine is changed. The therapy lasts no longer than 10 days.

It is advisable to start the treatment of diarrhea with probiotics and enterosorbents, only if the disease is severe or there is no effect, Furazolidone can be taken within 2-3 days of therapy. In the absence of its result, the patient is transferred to antibiotics Azithromycin, Imipenem, Amikacin.

Application for cystitis

To treat inflammation of the bladder (cystitis), tablets or granules are used to make a suspension. They are taken orally after meals, washed down with a glass of water. Treatment of cystitis is combined with the intake of vitamins of group B. During therapy, 0.1 g is taken 4 times a day, after 3-4 days they take a break, then repeat the course for the same period. The maximum therapeutic dose is 16 tablets.

With pyelitis and pyelonephritis - inflammation of the kidneys caused by streptococci or staphylococci, treatment with Furazolidone is accompanied by taking antibiotics from the group of fluoroquinolones, oxyquinolines, sulfonamides, phosphonic acid. Additionally, pain relievers, antipyretic drugs are shown. Non-steroidal anti-inflammatory drugs are not recommended.


Children under 4 years of age are especially susceptible to intestinal infections, since they have not yet developed a strong immune system. The child's body cannot fully develop antibodies to microbes, which leads to intoxication of the entire digestive system. To eliminate the infection, use "Furazolidone". This effective, but still toxic drug is given to babies strictly according to the doctor's prescription.

The principle of the drug Furazolidone

"Furazolidone" is an antimicrobial and antiprotozoal agent from the Nitrofuran group, prescribed to children mainly to fight intestinal infections. Unlike other drugs, "Furazolidone" not only eliminates pathogenic flora, but also strengthens local immunity, stimulates the body's independent fight against infection.

Addiction to "Furazolidone" develops slowly. The drug is effective against:


The drug in a minimal amount quickly enters the bloodstream through the gastrointestinal tract. The active components remain in the blood for 8 hours after taking the drug. The medicine destroys the membrane and the respiratory apparatus of microorganisms, preventing their reproduction. The child's well-being improves from the first days of treatment.

"Furazolidone" does not accumulate in the body, but is metabolized in the liver, which is why it is prescribed for babies. In some cases, the amount of the drug in the intestines exceeds the norm, which does not pose a danger to the child. Inactive chemical compounds and furazolidone in unchanged form are rapidly excreted through the kidneys.

Forms of drug release

"Furazolidone" has 2 pharmacological forms:


  1. Yellow flat-cylindrical tablets. Each tablet contains 50 mg of furazolidone. The drug is available in blisters of 10 tablets each. The package contains up to 5 records. Also, the medicine is sold in plastic jars of 50 tablets each. It is prescribed for children over 3 years old.
  2. Granules. The yellow and green particles have a lower concentration of active substance than the previous form. Used to prepare a suspension for the treatment of children from 1 year old. The package contains a plastic bottle with 50 g of granules and a measuring spoon.

When is it used?

According to the instructions, the use of "Furazolidone" is indicated for:

Dosage and method of administration

The dose of "Furazolidone" is determined by the doctor based on the patient's age and the degree of the disease. If the dosage is observed, the medication does not affect the work of the central nervous system and does not slow down the speed of psychomotor reactions. Sometimes taking the medicine leads to the development of polyneuritis - loss of sensitivity of the peripheral nerves. To avoid complications, "Furazolidone" is prescribed to children together with vitamin B.

Tablets

The tablets are used topically and orally. In the first case, the medication is used from the first month of a baby's life to prepare solutions for lotions that are applied to wounds. For internal use, the daily dose is calculated based on the proportion of 10 mg of the drug / 1 kg of the child's weight, dividing it into 4 doses. The medicine is taken after meals.

The therapeutic effect is observed 2 days after the start of treatment with "Furazolidone". As a rule, the duration of therapy does not exceed 10 days, but in some cases the doctor may increase it. If, within a week after the start of therapy, the baby's condition does not return to normal, it means that the causative agent of the pathology is immune to the drug. In this case, you need to find another medicine.

Suspension granules

To prepare a suspension, you need to pour boiled water into a bottle with granules up to the 100 ml mark. The liquid is taken in the same regimen as the tablets, but in a different dosage. Babies under 2 years old are given 5 ml of medicine, increasing the dosage by 1 ml every year. After pre-shaking, the suspension is taken after meals.

Regardless of the form of medication used, the child's diet should be limited during the treatment period. It is necessary to exclude from the diet foods rich in tyramine: fatty broths, hard cheese, herring, liver, smoked meats, stew, chocolate, strong tea and coffee. Treatment of infectious pathologies of the gastrointestinal tract is accompanied by intestinal upset, which can be avoided with the help of drugs with enzymes and probiotics.

The therapy is continued for as many days as the doctor has prescribed. You do not need to stop taking the medication even if your child is getting better. The disappearance of the symptoms of intoxication does not indicate the complete elimination of the pathogenic flora that provoked it. Premature refusal of the medication leads to the resumption of the infection with greater force.

How safe is the drug for children?

Safety is the determining criterion for choosing a drug for the treatment of gastrointestinal disorders in children in the first months of life.

The high efficiency of "Furazolidone" is combined with a low likelihood of side effects. Complications are associated with an overdose and taking the drug in the presence of contraindications.

Side effects

  • nausea and vomiting;
  • decreased appetite;
  • diarrhea;
  • dizziness and headache;
  • weakness and decreased activity;
  • drowsiness;
  • irritability;
  • local allergic reactions - rash and itching of the skin.

If mild side effects occur, you can divide the daily dose of the drug into 5-6 doses. It must be remembered that "Furazolidone" is toxic, and therefore it must be taken after meals. It is better to drink the medicine together with sorbents: activated carbon, "Smekta", "Sorbeks". To prevent the occurrence of allergies, the baby is given antihistamines.

Overdose

"Furazolidone" used to eliminate intoxication, if used incorrectly, leads to severe drug poisoning. In such cases, a worsening of the course of the underlying pathology is most often noted, but it also develops:

  • shortness of breath and cough;
  • convulsions;
  • pain in the epigastric region;
  • hyperthermia;
  • liver intoxication;
  • polyneuritis;
  • excess and decrease in hemoglobin in the blood, which is especially dangerous for a one-year-old baby.

If there are signs of an overdose, you should immediately consult a doctor. Due to the lack of an antidote to "Furazolidone", these symptoms are eliminated by washing the stomach, taking sorbents and laxatives. In severe drug poisoning, restoration of the water-electrolyte balance is shown.

Contraindications

"Furazolidone" is a toxic drug and can worsen the course of some somatic diseases.

It is unacceptable to take medication in the presence of the following contraindications:

  • hypersensitivity of the patient to the components of the drug;
  • severe pathologies of the liver and kidneys;
  • neurological disorders;
  • lactase deficiency and lack of glucose-6-phosphate dehydrogenase;
  • age up to one year.

Interaction with other drugs

When giving Furazolidone to children, one must remember about its ability to react with certain drugs. To avoid sudden surges in blood pressure, this medication is not prescribed with antidepressants and vasoconstrictors. The combination of "Furazolidone" with the antibiotics "Ristomycin" and "Chloramphenicol" provokes circulatory disorders.

Children, especially at a young age, are very susceptible to various infections, including intestinal infections. This is due to the fact that some factors, such as poor-quality food, taking medications and others, against the background of an immature immune system, can provoke the development of the disease. With diseases of the gastrointestinal tract, it is imperative to fight. Very often the drug Furazolidone comes to the rescue. How effective is it for treating children and is it safe for little patients?

The action and effectiveness of the drug

Furazolidone is a drug from the nitrofuran group that has antimicrobial activity. It has the greatest effect on gram-positive bacteria that cause infections of the gastrointestinal tract such as salmonellosis, dysentery, foodborne diseases, that is, food poisoning of poor quality.

Furazolidone is not very effective against the causative agents of purulent diseases, therefore it is practically not used for their treatment.

The main feature of Furazolidone is that bacteria addiction to it develops very slowly. This is due to its high efficiency. However, most often the remedy is prescribed in combination with other antibacterial drugs. Once in the intestines, the drug is rapidly absorbed and dispersed through the tissues, then decomposed in the liver into metabolic products and excreted in the urine or feces.

Composition and dosage forms

Furazolidone is available in the form of tablets and granules for the preparation of a suspension for oral administration.

Furazolidone is an antibacterial drug recommended for the treatment of gastrointestinal tract infections

The drug in the form of a suspension is allowed to be given to children according to indications after the first month of life. Tablets are contraindicated for up to 3 years. The release forms also differ in the concentration of the active substance: the content of furazolidone in the granules is lower. In addition, the following auxiliary components are included in the composition of the medicinal product:

  • calcium stearate;
  • polysorbate;
  • sucrose;
  • lactose;
  • potato starch.

Indications for use

Furazolidone is effective against infectious diseases of the gastrointestinal system. A pediatrician can prescribe a drug to a child in the following cases:

  • foodborne diseases (poisoning);
  • dysentery;
  • giardiasis;
  • cholera;
  • paratyphoid;
  • rotavirus infection.

In addition, the drug is used in the treatment of Trichomonas colpitis and urethritis, as well as for the healing of infected burns and wounds.

Furazolidone is used for the symptomatic treatment of diarrhea in children from a very young age.

Contraindications, side effects and interactions with other drugs

According to the instructions, Furazolidone has the following contraindications:

  • hypersensitivity or individual intolerance to the components of the drug;
  • severe liver failure;
  • kidney disease with impaired function;
  • diseases of the nervous system;

Many parents are interested in the safety of the drug for the child's body. The negative effect of Furazolidone is very rare, and the effectiveness is quite high. Side effects can be as follows:

  • allergic reactions, which are manifested by rashes, redness and itching of the skin;
  • nausea and vomiting;
  • decreased appetite.

In case of an overdose, the risk of developing complications of existing pathologies increases. Also, an excess of the drug can provoke toxic liver disorders (acute toxic hepatitis) and some nervous diseases of the extremities (polyneuritis).

If the baby has received a large dose of the drug, an urgent need to consult a doctor. Usually, gastric lavage is prescribed, in especially severe cases, hemodialysis is required - a method of blood purification using an "artificial kidney" apparatus.

Furazolidone is forbidden to be taken together with antidepressants and drugs containing ethanol, amphetamine, ephedrine, phenylephrine.

Instructions for use

For children, Furazolidone is recommended in the form of granules for preparing a suspension. Before use, it is necessary to pour boiled water into the bottle with the substance to the indicated mark and dissolve the contents. Shake the bottle before each use.

The dosage regimen is determined solely by the pediatrician. The doctor is based on the individual indicators of the baby - his age and weight, diagnosis and the nature of the course of the disease. The duration of the course of treatment is 5 to 10 days. Furazolidone is taken 4 times a day after meals.

What can replace Furazolidone for children

In the event of an allergic reaction or ineffectiveness of the drug, the doctor may prescribe another drug with a similar pharmacological effect to the baby.

Substitute drugs - table

Name Active substance Release form Indications Contraindications At what age is allowed approximate cost
Befungin
  • colbate chloride;
  • chaga extract.
oral solution
  • chronic gastritis;
  • gastrointestinal atony;
  • stomach ulcer;
  • asthenic conditions;
  • cachexia;
  • postoperative period.
from 1 year185 rubles
Enterofurilnifuroxazide
  • suspension for oral administration;
  • capsules.
hypersensitivity and individual intolerance to the components of the drug
  • suspension for oral administration - from 1 month;
  • capsules - from 2 years old.
  • suspension - 380 rubles;
  • capsules - 310 rubles.
Stopdiarnifuroxazide
  • tablets;
  • suspension for oral administration.
acute or chronic infectious diarrheahypersensitivity and individual intolerance to the components of the drug
  • tablets - from 2 years old;
  • suspension for oral administration - from 2 months.
  • tablets - 210 rubles;
  • suspension - 320 rubles.
Negronalidixic acidtablets
  • gastrointestinal infections;
  • cholecystitis;
  • pyelonephritis;
  • cystitis;
  • urethritis.
  • hypersensitivity and individual intolerance to the components of the drug;
  • dysfunction of the kidneys and liver;
  • epilepsy;
  • severe form of cerebral atherosclerosis;
  • deficiency of glucose-6-phosphate dehydrogenase.
from 2 years oldon request in pharmacies